IIVS | Assays Genetic Toxicology
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Observation Spots Available for 2018 Practical Methods Workshop

August 23, 2017
It's not too late to register for the 2018 Practical Methods in In Vitro Toxicology Workshop, Jan,16-19, at IIVS in Gaithersburg, MD. Observation spots are available for the intensive four-day workshop. Gain the scientific information and expertise you need to strategically integrate non-animal methods within your testing program.  Register now....

Webinar: How GLPs Enhance the Quality of Regulated and Non-Regulated Toxicology

October 18, 2016
This one-hour webinar, led by IIVS Director of Quality and Compliance, introduces some of the concepts of Good Laboratory Practices (GLPs) designed to promote study and data integrity within an in vitro toxicology framework. Applying these concepts within your own laboratory should aid in production of robust, repeatable studies. View Slides...

Reconstructed Skin Micronucleus (RSMN)

August 24, 2016
Reconstructed Skin Micronucleus (RSMN) Using the EpiDerm™ Reconstructed Human Epidermis Model RSMN is used to evaluate the genotoxicity potential of the test article to the EpiDerm™ Skin Model. Genotoxicity potential is determined by assessing whether the micronucleus frequency in tissues exposed to the test article showed a statistically significant increase relative to the tissues exposed to the solvent (negative) control. Evaluate the genotoxic potential of new ingredients and chemicals at exposure-relevant doses RSMN determines the skin genotoxicity/mutagenicity potential of a test substance...

Next Generation Tobacco Products

August 24, 2016
IIVS has a long-standing history of working with various industries to help establish or utilize in vitro models for the prediction of risk and the assessment of products under development. With the Food and Drug Administration extending its authority to all tobacco products (including e-cigarettes, cigars, and hookah) the tobacco industry is faced with the task of assessing product safety for product development and regulatory submission. Further, the manufacture of tobacco products may entail risk to workers that come in...

Specialty Chemical

August 24, 2016
Specialty chemicals are chemical products identified on the basis of their performance or function, rather than their composition. They can be single-chemical entities or formulations and cover a wide range of product categories such as consumer products, cosmetics, food additives, manufacturing, etc. As a result, testing for these chemicals can include a wide range in the irritation spectrum, from materials that are classified as mild irritants to those that are designated as corrosive. The testing needs also cover a wide range...

Evaluation Of A Novel Micronucleus Assay Using A Human 3-D Skin Model, EpiDerm™

January 1, 2006
Source: Presented at the Society of Toxicology Annual Meeting, 2006...