IIVS, Non Animal Testing, Alternative Test Methods, In Vitro Toxicology | Industries Household & Consumer Products
59
archive,tax-industry,term-household-consumer-products,term-59,ajax_fade,page_not_loaded,,qode_grid_1300,footer_responsive_adv,hide_top_bar_on_mobile_header,qode-content-sidebar-responsive,qode-child-theme-ver-,qode-theme-ver-11.0,qode-theme-bridge,wpb-js-composer js-comp-ver-4.11.2.1,vc_responsive

Archive

Abstract Deadline Extended for EUSAAT 2018

June 21, 2018
The 21st European Congress on Alternatives to Animal Testing & 18th Annual Congress of EUSAAT (European Society for Alternatives to Animal Testing) will take place in Linz, Austria, 23-26 September.  Submission deadlines for both oral and poster presentations have been extended to July 6. Erin Hill and Rodger Curren from IIVS are both speaking at the event. Learn more about the meeting, including the scientific program, invited speakers, and how to register.  ...

Abstract Deadline Extended for ESTIV 2018

June 18, 2018
The 20th International Congress on In Vitro Toxicology (ESTIV2018) happening in Berlin, 15-18 October, has extended their abstract submission deadline to July 1.  Several grants and bursaries are also still open to applicants until July 1, including the PETA International Science Consortium early-career scientist award. Learn more about the meeting, including the scientific program, invited speakers, and how to register.  ...

Holger Behrsing, PhD, Participates in Round Table Discussion on Non-Animal Approaches for Inhalation Toxicology

June 14, 2018
Holger Behrsing, PhD, was recently invited to participate in an expert round table discussion convened on the development and implementation of 21st century non-animal approaches to assess the toxicity of inhaled substances.  The discussion included perspectives from government, industry, nonprofit, and academic sectors on the advantages and challenges of using these approaches, ongoing efforts, and steps needed to gain widespread use and acceptance of these approaches. A transcript of the discussion has just been published in Applied In Vitro Toxicology, Vol....

IIVS BCOP Training Video – Spanish

October 16, 2017
This 13- minute video demonstrates how to perform the BCOP assay according to the Test Guidelines set forth for the assay by the Organization for Economic Co-operation and Development (OECD TG 437). The video focuses on steps that are critical to the success of the assay such as handling of the isolated cornea and removal of the test material from the cornea at the conclusion of the exposure time....

Momentum Grows for Modernizing the US EPA “Six-Pack” Battery of Acute Toxicity Tests

May 23, 2017
In the current global regulatory climate favorable for further advancement of in vitro test methods, the US Environmental Protection Agency (US EPA) is driving significant efforts in the United States. The latest endeavor targets the modernization of the battery of acute toxicity tests classically known as the “six-pack” (Fig. 1a). Known for many years as an “all in vivo” testing strategy for products registered under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), the six-pack has recently been revised to...

Webinar: How GLPs Enhance the Quality of Regulated and Non-Regulated Toxicology

October 18, 2016
This one-hour webinar, led by IIVS Director of Quality and Compliance, introduces some of the concepts of Good Laboratory Practices (GLPs) designed to promote study and data integrity within an in vitro toxicology framework. Applying these concepts within your own laboratory should aid in production of robust, repeatable studies. View Slides...

KeratinoSens (OECD 442D)

August 24, 2016
The KeratinoSensTM assay is a cell-based reporter gene assay that models the second key event in the Adverse Outcome Pathway for Dermal Sensitization, namely keratinocyte activation.  This approach measures the induction of luciferase under the control of the antioxidant response element (ARE) derived from the human AKR1C2 gene, and can be used in a Weight of Evidence approach as an alternative to animal testing methods for the purpose of hazard identification. IIVS has participated in validation studies led by the assay developer...

Eye Irritation Test (EIT, OECD 492)

August 24, 2016
The Eye Irritation Test (EIT) is an OECD-approved in vitro non-animal test method for identifying chemicals and mixtures that may be irritating to the corneal epithelium.. The test method utilizes an in vitro reconstructed human corneal epithelium (RhCE) model (EpiOcular™, MatTek Corp.), in an acute exposure assay to support international regulatory labeling requirements, according to the United Nations Globally Harmonized System of Classification and Labelling of Chemicals (UN GHS). The Eye Irritation Test can be used to support European Cosmetics dossier...

Household & Cleaning Products

August 24, 2016
The majority of the products manufactured or sold by the Household and Cleaning Products industry are subject to the requirements of the Federal Hazardous Substances Act (FHSA) which mandates that the product have appropriate safety labeling. The FHSA does not specifically require animal testing be conducted to determine if a hazard is present, but historically many companies have used animal testing for this purpose – and have continued to do so because of lack of familiarity with newer, non-animal  methods. IIVS...

Webinar: Regulatory Initiatives for New Approaches to Traditional Toxicity Testing

July 1, 2016
This one-hour webinar features presentations by Dr. Jennifer McLain, Deputy Director, Office of Pesticide Programs, Antimicrobial Division and IIVS CEO Dr. Rodger Curren. Dr. McLain discusses the EPA OPP's plans to reduce the use of animal testing in acute toxicity testing and provides suggestions on how stakeholders and EPA can cooperate to advance animal reduction goals. Dr. Curren then talks about IIVS' activities in developing the current non-animal strategy for eye irritation, and recent investigations into in vitro methods to...