Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS | Industries Pharmaceutical
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Archive

Tiered In Vitro Testing Strategy For Assessing The Ocular and Dermal Irritation/Corrosion Potential of Pharmaceutical Compounds

July 23, 2018
Read our latest publication with Bristol-Myers Squibb regarding a tiered testing strategy for occupational hazards of pharmaceutical intermediates now published in the Cutaneous and Ocular Toxicology Journal. Irritation reactions are a frequently reported occupational illness. The potential adverse effects of pharmaceutical compounds (PCs) on employees' eyes and skin can now be assessed using validated in vitro methods. Our overall aim is to reduce animal testing by replacing the historically utilized in vivo test methods with validated in vitro test methods which accurately determine the ocular...

Abstract Deadline Extended for EUSAAT 2018

June 21, 2018
The 21st European Congress on Alternatives to Animal Testing & 18th Annual Congress of EUSAAT (European Society for Alternatives to Animal Testing) will take place in Linz, Austria, 23-26 September.  Submission deadlines for both oral and poster presentations have been extended to July 6. Erin Hill and Rodger Curren from IIVS are both speaking at the event. Learn more about the meeting, including the scientific program, invited speakers, and how to register.  ...

Abstract Deadline Extended for ESTIV 2018

June 18, 2018
The 20th International Congress on In Vitro Toxicology (ESTIV2018) happening in Berlin, 15-18 October, has extended their abstract submission deadline to July 1.  Several grants and bursaries are also still open to applicants until July 1, including the PETA International Science Consortium early-career scientist award. Learn more about the meeting, including the scientific program, invited speakers, and how to register.  ...

View our Posters from SOT 2018

March 28, 2018
Thank you to all who visited our booth at the 2018 SOT meeting.  Our scientists presented several posters at the meeting. If you did not have an opportunity to view our posters, or would like to view them again, we now have them available here to view online. ...

IIVS at SOT 2018

February 8, 2018
IIVS will have several events and posters at the upcoming SOT meeting, March 11-15, in San Antonio, TX.  The events and three of our five posters focus on our respiratory toxicology program in support of our new laboratory that opened in 2017.  Other posters examine topics in phototoxicity.  Be sure to visit our booth at the meeting - Booth #533.   View more details on our events and posters at SOT....

Reducing the Use of Animals in Safety Testing: Strategic Roadmap Released

February 1, 2018
The National Toxicology Program, in collaboration with other US federal agencies, has published a strategic roadmap offering a new framework for the safety testing of drugs & chemicals aimed at reducing the use of animals. Read more....

IIVS BCOP Training Video – Spanish

October 16, 2017
This 13- minute video demonstrates how to perform the BCOP assay according to the Test Guidelines set forth for the assay by the Organization for Economic Co-operation and Development (OECD TG 437). The video focuses on steps that are critical to the success of the assay such as handling of the isolated cornea and removal of the test material from the cornea at the conclusion of the exposure time....

Multiparametric Image Analysis of Rat Dorsal Root Ganglion Cultures to Evaluate Peripheral Neuropathy-Inducing Chemotherapeutics

March 30, 2017
Chemotherapy-induced peripheral neuropathy (CIPN) is a major, dose-limiting adverse effect experienced by cancer patients. Advancements in mechanism-based risk mitigation and effective treatments for CIPN can be aided by suitable in vitro assays.  To this end, we developed a multiparametric morphology-centered rat dorsal root ganglion (DRG) assay. Read article....

The 3T3 Neutral Red Uptake Phototoxicity Test Training Video – Chinese

November 21, 2016
This new training video explores a cell-based method for assessing Phototoxicity – or the potential for chemicals to cause damage after being exposed to light. The method is used widely around the world by many industries, including the cosmetics and pharmaceutical sectors. Disclaimer: Please note that the procedures shown in this video were for demonstration purposes only and that all assay procedures, except the UVA/dark exposure, should be performed in a biological safety cabinet using aseptic techniques. Due to video production...

The 3T3 Neutral Red Uptake Phototoxicity Test Training Video – Portuguese

November 21, 2016
This new training video explores a cell-based method for assessing Phototoxicity - or the potential for chemicals to cause damage after being exposed to light. The method is used widely around the world by many industries, including the cosmetics and pharmaceutical sectors. Disclaimer: Please note that the procedures shown in this video were for demonstration purposes only and that all assay procedures, except the UV A/dark exposure, should be performed in a biological safety cabinet using aseptic techniques. Due to video...