IIVS | Mucosal
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Oral – Gingival Screening

The safety assessment of raw ingredients or finished products intended for human oral use or that can accidentally come in contact with humans’ oral tissues can be performed using in vitro testing platforms based on reconstructed tissue models. The oral irritation potential of oral care, pharmaceutical or tobacco products can be investigated using the tissue...

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Vaginal Irritation

The irritation potential of pharmaceutical, cosmetic and personal care products that are specifically formulated for application onto human mucosal tissues is evaluated using reconstructed tissue models such as EpiVaginal™ (MatTek Corporation, Ashland, MA, USA) or the Human Vaginal Epithelium (HVE) (EpiSkin, Lyon, France). The toxicity is determined by measuring the relative viability of the tissues...

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