The LuSens assay is a “me-too” assay which addresses the cellular event of keratinocyte activation, similar to the KeratinoSens assay (OECD 442D). It is a reporter gene bioassay using a human keratinocyte cell line. IIVS participated in an inter-laboratory study led by BASF to assess the transferability, reproducibility, and accuracy of the method. The results demonstrated an accuracy of greater than 80% in identifying skin sensitizers. The study was published in Toxicology in Vitro in 2016.