Systemic Toxicity Screening
Neutral Red Uptake
The Normal Human Epidermal Keratinocytes (NHEKs) Cytotoxicity Assay using a Neutral Red Uptake (NRU) viability endpoint is a 96-well cytotoxicity assay to assess the toxicity potential of a test material. The assay utilizes primary NHEK cells and may be used to predict either human lethal serum concentrations or in vivo rodent LD50 starting doses for acute oral systemic...
NHEK & 3T3
The 3T3 Neutral Red Uptake (NRU) Cytotoxicity Assay using a Neutral Red Uptake (NRU) viability endpoint is a 96-well cytotoxicity assay to assess the toxicity potential of a test material. The assay utilizes Balb/c 3T3 mouse fibroblasts to assess the systemic toxicity potential of a test material and may be used to predict in vivo rodent LD50 starting...