Use of alternative test methods in a tiered testing approach to address photoirritation potential of fragrance materials

03 Jan Use of alternative test methods in a tiered testing approach to address photoirritation potential of fragrance materials

Happy New Year! IIVS is pleased to greet 2022 with the announcement of a joint publication with the Research Institute for Fragrance Materials (RIFM) involving the evaluation of photoirritation potential of over 100 compounds. This effort, spanning the course of 7 years, involved a tiered testing approach with the application of 3 OECD test guidelines: TG 101, 432 and the recently accepted 498, which codifies the acceptance of Reconstructed human Epidermis as a model for assessing this endpoint.

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