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A Decision Tree For Acute Oral Toxicity: Implementing The Last Resort Requirement In Practice

September 22, 2026 Publication

Acute oral toxicity (AOT) testing is widely used for hazard identification in chemical safety assessment, but traditional animal methods are…

A Proposed Evaluation Of New Approach Methodologies For Dermal Toxicity Assessment Of Botanicals

September 22, 2026 Publication

Botanicals are widely used in topical formulations for cosmetics, hair care, and personal care products, reflecting consumer interest in plant-derived…

Lost In Nams-Lation: A Review Of Animal-Free Science Definitions

September 22, 2026 Publication

The use of terminology related to animal-free science has grown rapidly over the past two decades; however, definitions and interpretations…

Key Challenges For In Vitro Testing Of Oral Tobacco And Nicotine Products For Regulatory Applications: Recommendations For Using In Vitro Toxicity And Disease Models

September 22, 2026 Publication

The Institute for In Vitro Sciences (IIVS) has sponsored a series of workshops with the aim of developing recommendations for…

Key Challenges For In Vitro Testing Of Tobacco And Next Generation Products For Regulatory Applications: Recommendations For The Ames Test

September 22, 2026 Publication

The Ames bacterial mutagenesis assay (Ames test) has been used for more than 50 years, to help assess the safety…

June 2026 Newsletter

September 2, 2026 Newsletter

A collaboration between Institute for In Vitro Sciences (IIVS) and Epithelix has been established to expand access to advanced human-relevant…

March 2026 Newsletter

September 2, 2026 Newsletter

Read for information on upcoming events.

December 2025 Newsletter

September 2, 2026 Newsletter

As we reflect on the changes and announcements from US and international government agencies this year, we are excited about…

August 2025 Newsletter

September 2, 2026 Newsletter

Read to learn more about IIVS at WC13 and Eurotox, upcoming workshops, Spanish-language training, contributor spotlight, calls for methods for…

May 2025 Newsletter

September 2, 2026 Newsletter

We are thrilled to announce that IIVS is now offering the EpiSensA (Epidermal Sensitization Assay) as a GLP-compliant method in…

Defining Benchmarking in the Context of Safety Assessment of Personal Care and Cosmetic Products

August 3, 2026 Publication

The concept of benchmark materials in the personal care and cosmetic industry is often based on the positioning of prototypes…

Next-Generation Full-Thickness Human Skin Models Produced Using 3D Electrospun Scaffolds

August 3, 2026 Publication

In vitro full-thickness human skin (FT-Skin) models are important tools for testing of cosmetics and chemicals, screening of new pharmaceuticals,…