Results
Defining Benchmarking in the Context of Safety Assessment of Personal Care and Cosmetic Products
August 3, 2026 PublicationThe concept of benchmark materials in the personal care and cosmetic industry is often based on the positioning of prototypes…
Next-Generation Full-Thickness Human Skin Models Produced Using 3D Electrospun Scaffolds
August 3, 2026 PublicationIn vitro full-thickness human skin (FT-Skin) models are important tools for testing of cosmetics and chemicals, screening of new pharmaceuticals,…
Creating a Database of Reconstructed Oral Tissue Model Applications for Personal Care Industry and Beyond
August 3, 2026 PublicationThe personal care industry is an ever-expanding field of products that come into contact with our mouths daily, such as…
Using a Reconstructed Human Vaginal Epithelium Model to Assess Irritation
August 3, 2026 PublicationConsumers tend to think of personal lubricants as personal care products or cosmetics that are not tested using animals, but…
Confidence in New Approach Methods (NAMs)
August 3, 2026 PublicationReproducibility including independent ring trials remain essential for regulatory confidence in NAMs. Validation reform must not compromise data quality, robustness,…
The Impossible Made Possible Through the use of New Approach Methodologies
August 3, 2026 PublicationToxicological profiling is a critical component of the regulatory process required to inform the hazard characterisation and labelling of chemicals,…
Standards of Good Practices for the Conduct of In Vitro Toxicity Studies
December 19, 2025 PublicationThe field of in vitro toxicity studies presents the opportunity for great innovation while providing many scientific challenges. This chapter…
Advanced In Vitro Systems Available for Respiratory Toxicology
December 19, 2025 PublicationIncreasing concerns in respect to the transferability of data from animal studies to real human health effects further supported by…
Assessment of Phototoxicity Potential of Botanicals as Cosmetic Ingredients Using the In Vitro 3T3 Neutral Red Uptake Phototoxicity Test
December 19, 2025 PublicationCosmetics and personal care products are frequently formulated with botanical ingredients due to their beneficial properties, the nature of their…
New Horizons in Skin Sensitization Assessment of Complex Mixtures: The Use of New Approach Methodologies Beyond Regulatory Approaches
December 19, 2025 PublicationSkin sensitization is a complex biological process induced by a wide range of chemicals, from single molecules to complex mixtures…
A Proof-of-Concept for Safety Evaluation of Inhalation Exposure to Known Respiratory Irritants Using In Vitro and In Silico Methods
December 19, 2025 PublicationThere is increased interest in developing non-animal test systems for inhalation exposure safety assessments. However, defined methodologies are absent for…
New Approach Methodologies (NAMs) for the In Vitro Assessment of Cleaning Products for Respiratory Irritation: Workshop Report
August 22, 2025 PublicationThe use of in vitro new approach methodologies (NAMs) to assess respiratory irritation depends on several factors, including the speci…