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Optimizations of the Reconstructed Human Epidermis-Based Phototoxicity Testing to Evaluate the Safety of Long-Lasting Cosmetic Products

January 10, 2025 Publication

The safety of cosmetic products coming in contact with consumers’ skin is often assessed using New Approach Methodologies, which include…

November 2024 Newsletter

January 8, 2025 Newsletter

Our Respiratory Toxicology team has had a productive year, staying at the forefront of the latest industry developments while also…

September 2024 Newsletter

January 8, 2025 Newsletter

If you will be at EUROTOX, September 8-11, stop by BOOTH #34 to speak with IIVS President, Amanda Ulrey and…

A Proof-of-Concept for Safety Evaluation of Inhalation Exposure to Known Respiratory Irritants Using In Vitro and In Silico Methods

January 8, 2025 Publication

There is increased interest in developing non-animal test systems for inhalation exposure safety assessments. However, defined methodologies are absent for…

Building Confidence and Transparency Into a New Validation Paradigm

November 26, 2024 Poster/Presentation

For the last two decades, validation management organizations have evaluated new test methods according to the OECD’s Guidance Document 34:…

Human relevance of in vivo and in vitro skin irritation tests for hazard classification of pesticides

September 24, 2024 Publication

Test methods to inform hazard characterization and labeling of pesticides to protect human health are typically conducted using laboratory animals,…

The Fibrotic Phenotype of Human Precision-Cut Lung Slices Is Maintained after Cryopreservation

September 24, 2024 Publication

Human precision-cut lung slices (hPCLS) prepared from fibrotic lungs recapitulate the pathophysiological hallmarks of fibrosis. These hallmark features can also…

Deriving a point of departure for assessing the skin sensitization risk of wearable device constituents with in vitro methods

September 24, 2024 Publication

Wearable devices are in contact with the skin for extended periods. As such, the device constituents should be evaluated for…

Approaches to Evaluation of Solvents for use in Photosafety Testing

March 20, 2024 Poster/Presentation

New Approach Methodologies (NAMs) are routinely used in photosafety testing to evaluate if a test compound has the potential to…

Refinement and Optimization of the Photo-KeratinoSens™ Assay to Evaluate Photoallergy Potential

March 20, 2024 Poster/Presentation

Identification of test chemicals that have the potential to become more reactive, more toxic, or may become phototoxic upon application…

IIVS 2023 Impact Report

March 20, 2024 IIVS News

I am happy to present to you the Institute for In Vitro Sciences’ (IIVS) 2023 annual report, marking my first…

SOT 2024 Newsletter

February 28, 2024 Newsletter

Please visit us at booth #1232 during ToxExpo. We have exciting information to share about new assays, test guidelines and…