Results
A Proof-of-Concept for Safety Evaluation of Inhalation Exposure to Known Respiratory Irritants Using In Vitro and In Silico Methods
December 19, 2025 PublicationThere is increased interest in developing non-animal test systems for inhalation exposure safety assessments. However, defined methodologies are absent for…
New Approach Methodologies (NAMs) for the In Vitro Assessment of Cleaning Products for Respiratory Irritation: Workshop Report
August 22, 2025 PublicationThe use of in vitro new approach methodologies (NAMs) to assess respiratory irritation depends on several factors, including the speci…
Evaluation of a Non-Animal Toolbox Informed by Adverse Outcome Pathways for Human Inhalation Safety
August 22, 2025 PublicationThis work evaluated a non-animal toolbox to be used within a next-generation risk assessment (NGRA) framework to assess chemical-induced lung…
Development of Preliminary Candidate Surface Guidelines for Air Force-Relevant Dermal Sensitizers Using New Approach Methodologies
August 22, 2025 PublicationAllergic contact dermatitis (ACD) is an immunologic reaction to a dermal chemical ex-posure that, once triggered in an individual, will…
PETA Science Group, Colgate, and IIVS Team Up to Provide Training on Non-Animal Toxicity Testing
May 16, 2025 Press ReleaseGaithersburg, Md.— This week, five scientists from India will attend a globally recognized, non-animal toxicology training course in the United…
Micronucleus Induction by 5-Methoxypsoralen in the Photo Reconstructed Skin Micronucleus Assay
March 28, 2025 Poster/PresentationTo address a lack of suitable non-animal tools to screen novel ingredients in personal care products for mutagenic/clastogenic activity after…
Addressing Key Factors in Cryopreservation Method Development Ensures Robust Performance for Human Precision-cut Lung Slices
March 28, 2025 Poster/PresentationAs new approach methodologies (NAMs) are increasingly explored to identify dependable and accurate non-animal alternatives to predict human toxicities, several…
Genotoxicity Evaluation of Fragrances and Botanicals using ToxTracker Assay
March 28, 2025 Poster/PresentationThe ToxTracker® assay has gained attention as a second tier non-animal test method to the standard battery of in vitro…
Transfer and Refinement of the Reactive Oxygen Species (ROS) Assay to Evaluate Photoreactivity Potential
March 28, 2025 Poster/PresentationPhotoreactivity evaluation is one of the initial screenings in a photosafety assessment that can identify compounds which may have the…
Introducing a New Photoreactivity Assay
March 12, 2025 NewsletterIIVS is excited to announce the successful transfer of the Reactive Oxygen Species (ROS) photoreactivity assay into our laboratory. This…
Optimizations of the Reconstructed Human Epidermis-Based Phototoxicity Testing to Evaluate the Safety of Long-Lasting Cosmetic Products
January 10, 2025 PublicationThe safety of cosmetic products coming in contact with consumers’ skin is often assessed using New Approach Methodologies, which include…
November 2024 Newsletter
January 8, 2025 NewsletterOur Respiratory Toxicology team has had a productive year, staying at the forefront of the latest industry developments while also…