March 28, 2018
The US-FDA has regulatory authority over tobacco products, including conventional cigarettes and next generation products
(NGPs) such as e-cigarettes and tobacco heating products (THPs). There is a desire by the industry, regulator and animal
protection organizations to incorporate non-animal test methods for tobacco product and NGP assessment. When assessing
respiratory effects in vitro, reliable exposure systems that deliver aerosols to cellular/tissue cultures at the air-liquid interface
are needed.