The safety assessment of raw ingredients or finished products intended for human oral use or that can accidentally come in contact with humans’ oral tissues can be performed using in vitro testing platforms based on reconstructed tissue models. The oral irritation potential of oral care, pharmaceutical or tobacco products can be investigated using the tissue...
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The irritation potential of pharmaceutical, cosmetic and personal care products, medical devices and related consumables (such as lubricants)* that are formulated for application onto human cervical or vaginal tissues can be evaluated using reconstructed organotypic models representative of human ecto-cervical and vaginal tissue. These models overcome some of the disadvantages of monolayer culture by the...
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