The Institute for In Vitro Sciences (IIVS) provides robust test systems and assays to detect the adverse effects of diverse materials, including pharmaceuticals targeting COVID-19. The IIVS Respiratory Toxicology Program offers testing services using cutting edge 3D pulmonary models – in addition to human 2D primary cells and lines – such as reconstructed human airways and precision-cut human lung slices that contain multiple cell types including immune competent macrophages. These systems allow the detection of acute toxic responses such as oxidative stress, cytotoxicity, and inflammation (among others), as well as long term chronic exposure responses not possible using other models. Let IIVS help you determine the safety of your therapeutics throughout your development program. Visit our Respiratory Toxicology webpage to learn more!