Viability

Summary

Toxicity leading to loss of tissue viability results in loss of NADH or NAD(P)H dehydrogenase activity. The tissue enzyme activity serves as a marker of viability and can be assessed using various dyes, like WST-8. Comparing the amount of the formazan generated by dehydrogenases is directly in proportion to the numbers of living cells.

Assay Type

Tissue Health

Test Systems

2D Cells

3D RHuA

3D hPCLS

Exposure Systems

Solubles

Digital Dispensing

Aerosols

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