Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS | 2016 September
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September 2016

International Harmonization and Cooperation in the Validation of Alternative Methods

September 27, 2016
The development and validation of scientific alternatives to animal testing is important not only from an ethical perspective (implementation of 3Rs), but also to improve safety assessment decision making with the use of mechanistic information of higher relevance to humans. To be effective in these efforts, it is however imperative that validation centres, industry, regulatory bodies, academia and other interested parties ensure a strong international cooperation, cross-sector collaboration and intense communication in the design, execution, and peer review of validation...

Implementation of New Test Methods into Practical Testing

September 27, 2016
New toxicology test methods, especially those using in vitro methods, are continually being developed. Some are used by industry for screening purposes; others are eventually validated for regulatory use. However, for a new test method to be firmly adopted by industry it must be readily available, generally through an in-house industry laboratory, an academic laboratory, or a contract research organization. Read chapter.  ...

IIVS Announces Suite of Non-Animal Methods to Reduce Animal Testing for Skin Sensitization

September 6, 2016
GAITHERSBURG, MD – September 6, 2016 – In response to a newly published OECD Test Guideline, IIVS announces the addition of the Human Cell Line Activation Test (h-CLAT, OECD TG 442E) to its suite of non-animal assays to determine skin sensitization. The assessment of skin sensitization has historically involved the use of laboratory animals; specifically guinea pigs and mice. In recent years, international research and validation efforts have paved the way for the use of non-animal methods. “Industry has provided the field...

IIVS e-News, September 2016

September 1, 2016
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