Author: Jane Ryan

The Bovine Corneal Opacity and Permeability (BCOP) assay is an ex vivo test for predicting ocular irritation. For regulatory classification, OECD Test Guideline (TG) 437 specifies that liquid and solid surfactants may be tested as 10% aqueous dilutions for 10 minutes, although alternate dilutions and...

GAITHERSBURG, MD - Determination of skin sensitization potential is a critical toxicological endpoint in the safety assessment of new chemicals. Although the Guinea Pig Maximization Test (GPMT) and in vivo Local Lymph Node assay (LLNA) have traditionally been used to assess skin sensitization, recent activity...