It is recommended that an evaluation of the impact of shipping of Reconstructed human Epidermis (RhE) tissues be conducted especially after long-haul airfreight shipments. The OECD Test Guideline 439 (OECD TG 439), In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method, recommends that users do so...
FDA’s recently launched Predictive Toxicology Roadmap calls for the optimization of non-animal methods for the safety evaluation of drugs, consumer products and medical devices. We have created an Industry Consortium comprised of manufacturers of personal lubricants/vaginal moisturizers and companies interested in the advancement of animal...
Among the topics discussed at the annual Scientific Advisory Committee on Alternative Toxicological Methods (SACATM) meeting held in early September was ways to encourage both regulators and regulated industry to use new approach methodologies (NAMs). The meeting brought together experts from academia, industry, and animal welfare organizations...
The 21st European Congress on Alternatives to Animal Testing & 18th Annual Congress of EUSAAT (European Society for Alternatives to Animal Testing) will take place in Linz, Austria, 23-26 September. Submission deadlines for both oral and poster presentations have been extended to July 6. Erin Hill...
The 20th International Congress on In Vitro Toxicology (ESTIV2018) happening in Berlin, 15-18 October, has extended their abstract submission deadline to July 1. Several grants and bursaries are also still open to applicants until July 1, including the PETA International Science Consortium early-career scientist award. Learn more about the...
To address ocular device induced phototoxicity, an in vitro 3T3 Neutral Red Uptake Phototoxicity test (OECD 432) for chemicals has been modified. Soft contact lenses formulated with three different photo-absorbing compounds and chemical solutions of these compounds were evaluated....
IIVS will have several events and posters at the upcoming SOT meeting, March 11-15, in San Antonio, TX. The events and three of our five posters focus on our respiratory toxicology program in support of our new laboratory that opened in 2017. Other posters examine...
[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text css=""]Oct 16, 2017 This 13-minute training video demonstrates how to perform the BCOP assay according to the Test Guidelines for the assay set forth by the Organization for Economic Co-operation and Development (OECD TG 437). The video focuses...
The use of non-whole animal test methods transforms the way regulatory requirements are applied in preclinical testing. Recent global regulatory initiatives emphasize the importance of transitioning to human relevant assays and test systems that do not use animals. When these methods are moved from research...
Presented at the 2017 World Congress on Alternatives and Animals in the Life Sciences (WC10) E. Hill, R. Curren, and G.-E. Costin Starting in December 2015, personal lubricants must receive pre-market approval from the US FDA Center for Devices and Radiological Health (CDRH) in order to be sold...