Results
Micronucleus Induction by 5-Methoxypsoralen in the Photo Reconstructed Skin Micronucleus Assay
March 28, 2025 Poster/PresentationTo address a lack of suitable non-animal tools to screen novel ingredients in personal care products for mutagenic/clastogenic activity after…
Addressing Key Factors in Cryopreservation Method Development Ensures Robust Performance for Human Precision-cut Lung Slices
March 28, 2025 Poster/PresentationAs new approach methodologies (NAMs) are increasingly explored to identify dependable and accurate non-animal alternatives to predict human toxicities, several…
Genotoxicity Evaluation of Fragrances and Botanicals using ToxTracker Assay
March 28, 2025 Poster/PresentationThe ToxTracker® assay has gained attention as a second tier non-animal test method to the standard battery of in vitro…
Transfer and Refinement of the Reactive Oxygen Species (ROS) Assay to Evaluate Photoreactivity Potential
March 28, 2025 Poster/PresentationPhotoreactivity evaluation is one of the initial screenings in a photosafety assessment that can identify compounds which may have the…
Building Confidence and Transparency Into a New Validation Paradigm
November 26, 2024 Poster/PresentationFor the last two decades, validation management organizations have evaluated new test methods according to the OECD’s Guidance Document 34:…
Approaches to Evaluation of Solvents for use in Photosafety Testing
March 20, 2024 Poster/PresentationNew Approach Methodologies (NAMs) are routinely used in photosafety testing to evaluate if a test compound has the potential to…
Refinement and Optimization of the Photo-KeratinoSens™ Assay to Evaluate Photoallergy Potential
March 20, 2024 Poster/PresentationIdentification of test chemicals that have the potential to become more reactive, more toxic, or may become phototoxic upon application…
Toxicity and Inflammatory Response to Common Magic Mouthwashes in a 3D Oral Reconstructed Tissue Model
November 8, 2023 Poster/PresentationMagic Mouthwash is a general term describing oral rinses prescribed by a doctor for the treatment of pain, inflammation, or…
Safety Assessment of Monographed OTC Cold/Cough Medicine Using an In Vitro Testing Platform Based on Human Reconstructed Oral Tissues
November 8, 2023 Poster/PresentationOver-the-counter (OTC) products are available to alleviate concurrent symptoms of colds and flu. They are primarily based on a combination…
A Laboratory Method to Measure Skin Surface Staining by Cigarette Smoke
October 20, 2023 Poster/PresentationExhaled or side-stream cigarette smoke (CS) may visually stain a consumer’s skin over time. Tobacco heating prod- ucts (THPs) and…
Ensuring the quality of a test system using the principles of Good In Vitro Method Practices (GIVIMP): A case study of cryopreserved human precision-cut lung slices
October 10, 2023 Poster/PresentationHuman precision-cut lung slices (hPCLS) are a highly relevant 3-dimensional model of the lung. They offer native architecture and cells…
Key Recommendations from GIVIMP for Test System Suppliers
October 10, 2023 Poster/PresentationThe Organization for Economic Cooperation and Development (OECD) guidance document on Good In Vitro Method Practices (GIVIMP) details a set…