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Incorporating GIVIMP Recommendations into Method Development, Use, and Transfer

August 30, 2023 Poster/Presentation

The demand for toxicology data from human-relevant, New Approach Methodologies (NAMs) continues to increase. Fortunately, the scientific community has responded…

IIVS Posters – SOT 2023 Annual Meeting

March 31, 2023 Poster/Presentation

IIVS presented several posters at SOT 2023. This post includes links to the full PDF versions of each poster presented.

Good In Vitro Method Practices Certification: A Roadmap for Implementation and Harmonization

October 7, 2022 Poster/Presentation

The Organization for Economic Cooperation and Development (OECD) guidance document on Good In Vitro Method Practices (GIVIMP) details a set…

IIVS Workshop Series: Identification, Discussion and Recommendations for the Optimal Generation and Use of In Vitro Genotoxicity Assay Data for Tobacco and Nicotine Products

October 18, 2019 Poster/Presentation

The Institute for In Vitro Sciences (IIVS) is sponsoring a series of workshops to identify, discuss and develop recommendations for…

Use of Ex Vivo Precision-Cut Lung SLices as a Screening Tool for Potential Respiratory Toxicity of E-Liquids

October 17, 2019 Poster/Presentation

The Family Smoking Prevention and Tobacco Control Act gave the FDA regulatory authority over next generation tobacco products (NGTP) such…

Evaluation of TRPV1 Activity to Assess the Eye Stinging Potential of Cosmetic Formulations

October 17, 2019 Poster/Presentation

The Transient Receptor Potential Vanilloid type 1 (TRPV1) receptor is one of the most well characterized pain-inducing receptors and has…

Promoting the Uptake of Alternatives to Animal Testing Through the Development of eLearning Tools

September 13, 2019 Poster/Presentation

In order to further promote the implementation of Directive 2010/63/EU, the European Commission issued calls for a number of related…

kDPRA: An in chemico Method to Characterize the Skin Sensitization Potency of Chemicals

September 13, 2019 Poster/Presentation

While the skin sensitization hazard of substances can readily be identified using non-animal methods, the classification of potency into UN…

Shipping Study to Evaluate the Performance of the LabCyte EPI-MODEL 24 Tissues for Use in the Skin Irritation Test (OECD TG 439) After Long-Haul Airfreight

March 18, 2019 Poster/Presentation

It is recommended that an evaluation of the impact of shipping of Reconstructed human Epidermis (RhE) tissues be conducted especially…

Regarding the References for Reference Chemicals of Alternative Methods

March 18, 2019 Poster/Presentation

The selection of reference and proficiency chemicals is an important component of method validation and proficiency evaluations. Reference chemicals are…

Next Generation Tobacco Products and Skin Staining

March 18, 2019 Poster/Presentation

Next generation tobacco and nicotine products (NGPs) such as electronic cigarettes (EC) and tobacco heating products (THP) have reduced toxicity…

Non-animal Vaginal Irritation Method Admitted into the US FDA Medical Devices Development Tool (MDDT)

October 18, 2018 Poster/Presentation

FDA’s recently launched Predictive Toxicology Roadmap calls for the optimization of non-animal methods for the safety evaluation of drugs, consumer…