Results
Next-Generation Tobacco and Nicotine Products: Substantiating Harm Reduction and Supporting Tobacco Regulatory Science
June 21, 2018 PublicationA framework for the assessment of novel next-generation tobacco and nicotine products with the potential to reduce health risks compared with…
Characterization of a Vitrocell VC1 Using Nicotine Dosimetry: An Essential Component Toward Standardized In Vitro Aerosol Exposure of Tobacco and Next Generation Nicotine Delivery Products
June 21, 2018 PublicationThe U.S. Food and Drug Administration has regulatory authority over tobacco products, including conventional cigarettes and next generation products (NGPs) such…
Know Your Skin Cells: III. The Melanocytes
February 1, 2018 IIVS NewsIIVS toxicologist and study director, Emilia Costin wrote about melanocytes, responsible for producing skin color for The Cosmetic Chemist. Read…
In Vitro Exposure Systems and Dosimetry Assessment Tools for Inhaled Tobacco Products: Workshop Proceedings, Conclusions and Paths Forward for In Vitro Model Use
August 17, 2017 PublicationIn 2009, the passing of the Family Smoking Prevention and Tobacco Control Act facilitated the establishment of the FDA Center…
Advances in Science: Next Generation of Lab Tools, Models and Testing Platforms Used in Predictive Toxicology
July 19, 2017 PublicationToxicology testing platforms represent the basis of the human health risk assessment process that determines whether a material or product may…
Navigating the Claim Substantiation Maze in Cosmetics Industry
June 15, 2017 PublicationRead this article by IIVS study director Dr. Gertrude-Emilia Costin and biologist Asha Shravanthi Pidathala in the June 2017 issue of Eurocosmetics. …
Assessment of In Vitro COPD Models for Tobacco Regulatory Science: Workshop Proceedings, Conclusions and Paths Forward for In Vitro Model Use
March 30, 2017 PublicationOn 8-10 December 2014, IIVS organised a workshop conference, entitled Assessment of In Vitro COPD Models for Tobacco Regulatory Science,…
Multiparametric Image Analysis of Rat Dorsal Root Ganglion Cultures to Evaluate Peripheral Neuropathy-Inducing Chemotherapeutics
March 30, 2017 PublicationChemotherapy-induced peripheral neuropathy (CIPN) is a major, dose-limiting adverse effect experienced by cancer patients. Advancements in mechanism-based risk mitigation and…
In Vitro Assessment of Skin Irritation Potential of Surfactant-based Formulations by Using a 3-D Skin Reconstructed Tissue Model and Cytokine Response
January 24, 2017 PublicationThe personal care industry is focused on developing safe, more efficacious, and increasingly milder products, that are routinely undergoing preclinical…
The Use of Human 3D Reconstructed Airway Cultures for Tobacco Product Evaluation: Precision Low-Volume Exposures at the Apical Site
January 10, 2017 PublicationWith a mandate to evaluate the dynamics of pulmonary exposure to inhaled materials such as tobacco-based products, researchers are employing complex,…
Trends in Regenerative Medicine: Repigmentation in Vitiligo Through Melanocyte Stem Cell Mobilization
December 28, 2016 PublicationVitiligo is the most frequent human pigmentary disorder, characterized by progressive autoimmune destruction of mature epidermal melanocytes. Of the current…
Decoding and Modulating the Color of Human Skin
November 22, 2016 PublicationThe constitutive color of human skin varies widely across the globe, from the very pale as in Celtic skin to…