IIVS' work with the China Food and Drug Administration (CFDA) and its subsidiary body, the National Institute for Food and Drug Control (NIFDC) has paid off with the recent approval of the T3 Neutral Red Uptake Phototoxicity Test, the first non-animal test method that can be used for safety tests in cosmetics sold in China. This article references IIVS's work with the CFDA and NIFDC over the last several years to provide training and education around non-animal methods for safety assessments in conjunction with China's ongoing efforts to modernize their testing requirements and reduce their reliance on animals.
Taiwan has passed a bill to ban cosmetics testing on animals. With a three-year implementation period in place, it will take effect from October 2019.
An adverse outcome pathway, or AOP, is a highly structured way of describing a toxicological process which can lead to an adverse health effect in humans or wildlife, caused by an unsafe exposure to a chemical substance. The first five adverse outcome pathways have now been published by experts. The AOPs are novel knowledge management tools in toxicology and are useful for supporting risk assessment to human health. They are also valuable for helping to avoid animal testing through the use of alternative methods.