Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS | Assays Respiratory Toxicology

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Archive

Effect of Acclimation Conditions on 3D Human in vitro ALI Airway Models: Exposure-induced Inflammatory Response and Sampling Location-specific Results

March 15, 2016
Source: SOT 2016... Acute Respiratory Toxicity | Bronchial/Tracheal | Household & Consumer Products | Tobacco

Detection of Inflammation and Parenchymal Damage Using Precision-cut Lung Slices

March 10, 2016
... Bronchial/Tracheal | Precision Cut Lung Slices (PCLS) | Pulmonary Models | Household & Consumer Products | Tobacco

3D Reconstructed Human Airway Models: Effect of Acclimation Conditions on Biomarker and Inflammatory Response Following Tissue Challenge

March 10, 2016
Source: TRSC 2015... Acute Respiratory Toxicity | Bronchial/Tracheal | Tobacco

Workshop Report: Assessment of In Vitro COPD Models for Tobacco Regulatory Science

July 10, 2015
Source: IIVS December 2014 Workshop See also In Vitro Exposure Systems and Dosimetry Assessment Tools for Inhaled Tobacco Products from our April 2016 workshop.... Acute Respiratory Toxicity | Bronchial/Tracheal | Chronic Respiratory Toxicity | Goblet Cell Hyperplasia | Pulmonary Models | Respiratory Toxicology | Tobacco

Evaluation of a Reconstructed Human Oral Buccal Tissue Model as a Testing Platform for Determining the Oral Irritation Potential of Tobacco Products

December 1, 2014
Source: Assessment of In Vitro COPD Models for Tobacco Regulatory Science... Bronchial/Tracheal | Chronic Respiratory Toxicity | Oral - Gingival Screening | Oral Buccal | Tobacco

Toxic Insult to Rat Precision Cut Lung Slices Increases Tissue Cytokine Levels and Activation of Macrophages, and Causes Acute Damage, While Prolonged Insult May Lead to Increased Deposition of Collagen – a Marker of Fibrosis

December 1, 2014
Source: Assessment of In Vitro COPD Models for Tobacco Regulatory Science... Bronchial/Tracheal | Inflammatory Cytokine Expression | Precision Cut Lung Slices (PCLS) | Tobacco

The Use of Precision-cut Lung Slices to Assess Inflammation, Parenchymal Damage, and Collagen Deposition: Three Markers of Tobacco Exposure-induced Pulmonary Toxicity