With a mandate to evaluate the dynamics of pulmonary exposure to inhaled materials such as tobacco-based products, researchers are employing complex, human, three-dimensional pulmonary models. Human reconstructed airway (RHuA) tissues present a platform that more closely resembles airways in vivo. Grown at the air–liquid interface (ALI), RHuA tissues...
Vitiligo is the most frequent human pigmentary disorder, characterized by progressive autoimmune destruction of mature epidermal melanocytes. Of the current treatments offering partial and temporary relief, ultraviolet (UV) light is the most effective, coordinating an intricate network of keratinocyte and melanocyte factors that control numerous...
On December 20, 2016, the U.S. Environmental Protection Agency (EPA)announced the start of a pilot program to evaluate the usefulness and acceptability of a mathematical tool (the GHS Mixtures Equation), which is used in the Globally Harmonized System of Classification and Labeling of Chemicals (GHS)....
PETA UK and PETA Netherlands staff attended a meeting in Hague last week at which Dutch Secretary of State for Economic Affairs Martijn van Dam announced his intention for the Netherlands to end the use of animals in safety tests for chemicals, food ingredients, pesticides,...
Composed of 11 technical institutes, the NIFDC is responsible for the registration and post market surveillance of drugs, traditional Chinese medicines, medical devices, food and cosmetics. In addition to inspecting and testing these products for safety, the NIFDC publishes National Reference Standards for testing methods...
IIVS and stakeholders around the world welcomed the announcement last month by the CFDA that data from a non-animal test method can now be used to substantiate the safety of cosmetics made in China. The test, known as the In Vitro 3T3 NRU Phototoxicity Test...
PETA is accepting proposals to award a VITROCELL® exposure system—valued at up to $100,000—to researchers who will use it to avoid testing on animals. The VITROCELL exposure system can be used to deliver aerosolized test substances to human lung cells to predict human health effects...
IIVS' work with the China Food and Drug Administration (CFDA) and its subsidiary body, the National Institute for Food and Drug Control (NIFDC) has paid off with the recent approval of the T3 Neutral Red Uptake Phototoxicity Test, the first non-animal test method that can...
The constitutive color of human skin varies widely across the globe, from the very pale as in Celtic skin to the very dark present in regions such as sub-Saharan Africa. There is a biologic player “hard at work” producing the pigments that generate great variations...