Robust non-animal models and assays for pulmonary toxicology are required to make competent product development and risk assessments for new materials requiring toxicity testing. Three in vitro assays (goblet cell hyperplasia [GCH], ciliary beat frequency [CBF], and MUC5AC quantitation) were evaluated for performance and reproducibility....
E-vapor product liquids contain a variety of ingredient combinations that should be assessed for human risk. One human lung-relevant testing platform with reasonable throughput, is human precision-cut lung slices (HuPCLS). HuPCLS are arguably the most complex non-animal model of the lung, retaining native architecture and...
While data are still being collected and analyzed, there were at least 1,300 accidental electronic liquid (e-liquid) exposures reported as of 2013. Deaths have occurred as a result of ingestion of e-liquid with the effects being attributed primarily to nicotine. The Food and Drug Administration (FDA)...
The US-FDA has regulatory authority over tobacco products, including conventional cigarettes and next generation products (NGPs) such as e-cigarettes and tobacco heating products (THPs). There is a desire by the industry, regulator and animal protection organizations to incorporate non-animal test methods for tobacco product and NGP assessment....
New data presented at the Society of Toxicology Annual Meeting (SOT) have demonstrated the potential of two different heat-not-burn tobacco products and e-cigarettes to reduce the risk of smoking-related diseases, in comparison to continued use of conventional cigarettes. One of those studies was by IIVS...
IIVS President, Erin Hill, and Business Development Manager, Brent Gilbert, will be at the upcoming NYSCC Suppliers Day 2018 in New York City on May 15-16. Stop by our booth (#973) to chat with us or contact us to set up a meeting....
Read the latest issue of our e-newsletter for information about our events and posters at the 2018 Society of Toxicology (SOT) Annual Meeting, presentations at upcoming meetings and more. View issue....
GAITHERSBURG, MD – March 1, 2018 – The Institute for In Vitro Sciences, Inc. (IIVS) announced that it has appointed Frank Gerberick, PhD as its Chief Scientific Advisor. With his expertise and knowledge of technological advances and industry trends, Dr. Gerberick will advise the organization’s...
IIVS will have several events and posters at the upcoming SOT meeting, March 11-15, in San Antonio, TX. The events and three of our five posters focus on our respiratory toxicology program in support of our new laboratory that opened in 2017. Other posters examine...
Featured in this issue is an article on how an integrated approach to skin sensitization testing can work for your testing program. a preview of IIVS events and posters at SOT, our recent collaboration with BASF to distribute the LuSens test in China, and more. ...