Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS |

01 Apr Evaluation of the Validated In Vitro Skin Irritation Test (OECD TG 439) for the Assignment of EPA Hazard Categories

Posted at 03:16h in Uncategorized by Jane Ryan 0 Comments

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Progress within the in vitro toxicology field has made available testing platforms based on reconstructed tissue models that are validated to address the skin corrosion and irritation endpoints. While the validated in vitro assays can be used for the hazard identification of chemicals irritant to...

01 Apr Improving Sensitivity of the NociOcular Assay to Evaluate Ion Channel Activation by Acidic Cosmetic Ingredients

Posted at 03:05h in Uncategorized by Jane Ryan 0 Comments

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Source: Pan-American Conference on Alternatives ...

01 Apr Improving the Accessibility and Efficiency of the Human Cell Line Activation Test

Posted at 02:59h in Uncategorized by Jane Ryan 0 Comments

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Source: Pan-American Conference on Alternatives...

01 Apr Mimicking Metabolism Using Human Microsomes in Two In Vitro Assays in Order to Predict the Sensitization Potential of Pro-haptens

Posted at 02:51h in Uncategorized by Jane Ryan 0 Comments

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Source: Pan-American Conference on Alternatives...

01 Apr The Assessment of Alternate Solvents for Use in the 3T3 Neutral Red Uptake (NRU) Phototoxicity Assay and the Influence of Solvents on the Prediction of Phototoxic Potential of Amiodarone

Posted at 01:48h in Uncategorized by Jane Ryan 0 Comments

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Source: Pan-American Conference on Alternatives...

17 Mar Evaluation of New Solvents for the Use in the Multi‐Dose Reconstructed Human EpiDermis (RhE) Phototoxicity Assay

Posted at 03:19h in Uncategorized by Jane Ryan 0 Comments

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The phototoxic potential of test materials after exposure to UVA/visible light is evaluated by the 3T3 Neutral Red Uptake Phototoxicity Assay using Balb/c 3T3 mouse fibroblasts (OECD TG 432). To address challenges related to testing of finished products or materials that are not completely soluble,...