Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS | Erin Hill
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Erin Hill Tag

Promoting the Uptake of Alternatives to Animal Testing Through the Development of eLearning Tools

September 13, 2019
In order to further promote the implementation of Directive 2010/63/EU, the European Commission issued calls for a number of related projects last year. One of these projects is aimed at facilitating the uptake of non-animal alternatives by developing two e-learning modules. The contract for this project was awarded to a consortium consisting of SYRCLE, the Swiss 3R Competence Centre, lnstitute for ln Vitro Sciences, Pharma Launcher and Ecorys UK. This consortium will develop two modules, i.e., one eLearning module focused...

kDPRA: An in chemico Method to Characterize the Skin Sensitization Potency of Chemicals

September 13, 2019
While the skin sensitization hazard of substances can readily be identified using non-animal methods, the classification of potency into UN GHS sub-categories 1A and 1B remains challenging. The kinetic direct peptide reactivity assay (kDPRA) is a modification of the DPRA (OECD TG 442C) wherein the reaction kinetics of a test substance towards a synthetic cysteine-containing peptide is evaluated. For this purpose, several concentrations of the test substance are incubated with the synthetic peptide for several incubation times at 25°C. After...

IIVS Receives Support for Non-Animal Testing From RIFM

September 9, 2019
September 10, 2019, Gaithersburg, MD – The Institute for In Vitro Sciences, Inc. (IIVS) is excited to announce that it has received a grant from the Research Institute for Fragrance Materials (RIFM) to support its mission to promote non-animal methods. The grant will be used to purchase equipment that will enable IIVS to expand capabilities and offer several non-animal tests in compliance with Good Laboratory Practices. “RIFM and IIVS have a long history of working together to identify non-animal testing approaches...

IIVS and Partners Win Contract from the European Commission to Develop Training for Non-animal Testing Methods

July 16, 2019
July 16, 2019, Gaithersburg, MD – The Institute for In Vitro Sciences (IIVS) is pleased to announce it is part of a winning consortium, headed by SYRCLE (the Systematic Review Centre for Laboratory animal Experimentation), to develop interactive eLearning training modules. The application of the Replacement, Reduction and Refinement of animal testing, commonly known as “The 3Rs,” is a requirement in the European Union Directive 2010/63/EU “on protection of animals used for scientific purposes.” Training is an essential component to...

Non-animal Vaginal Irritation Method Admitted into the US FDA Medical Devices Development Tool (MDDT)

October 18, 2018
FDA’s recently launched Predictive Toxicology Roadmap calls for the optimization of non-animal methods for the safety evaluation of drugs, consumer products and medical devices. We have created an Industry Consortium comprised of manufacturers of personal lubricants/vaginal moisturizers and companies interested in the advancement of animal alternatives working collaboratively with stakeholders and the US FDA to develop an in vitro testing approach that could be used in place of the rabbit vaginal irritation (RVI) in pre-market submissions....