As we reflect on the changes and announcements from US and international government agencies this year, we are excited about the opportunities that 2026 will bring. We are deeply grateful to all our contributors, collaborators, clients, and supporters for your continued partnership in advancing science...
Read to learn more about IIVS at WC13 and Eurotox, upcoming workshops, Spanish-language training, contributor spotlight, calls for methods for validation, and recent publications....
We are thrilled to announce that IIVS is now offering the EpiSensA (Epidermal Sensitization Assay) as a GLP-compliant method in our sensitization testing portfolio. EpiSensA offers a reliable, human-relevant method for assessing skin sensitization potential, increasing our ability to provide New Approach Methodology (NAM) testing...
The concept of benchmark materials in the personal care and cosmetic industry is often based on the positioning of prototypes relative to the leading brand within a given product category. The main points of comparison are the market ranking, performance regarding consumers’ perception, aesthetics, cost,...
In vitro full-thickness human skin (FT-Skin) models are important tools for testing of cosmetics and chemicals, screening of new pharmaceuticals, and human disease modeling research. However, these skin models commonly utilize animal-derived collagen as a main structural element of the stromal matrix. Animal-derived collagen constructs...
The personal care industry is an ever-expanding field of products that come into contact with our mouths daily, such as lipsticks, toothpastes, mouth-washes, and whitening products. With a multitude of new products being released each year, how are they all being evaluated for consumer safety?...
Consumers tend to think of personal lubricants as personal care products or cosmetics that are not tested using animals, but the regulatory classification and hence the testing requirements for these products vary by country. For example, in the United States, regulations and guidance classify personal...
Reproducibility including independent ring trials remain essential for regulatory confidence in NAMs. Validation reform must not compromise data quality, robustness, or legal defensibility. Context of use should be operationalized to distinguish formal regulatory- and flexible case-specific use. Short-cuts on validation risks irreproducibility, regulatory failure,...
Toxicological profiling is a critical component of the regulatory process required to inform the hazard characterisation and labelling of chemicals, thus guiding their safe handling and use. Skin irritation is a key endpoint for regulatory registrations, traditionally assessed by using the Draize rabbit test, which...
Leiden, The Netherlands and Gaithersburg, MD, USA — 17 July 2026 — Toxys and the Institute for In Vitro Sciences (IIVS) are pleased to announce an expanded strategic partnership aimed at accelerating the adoption of innovative in vitro methods for chemical safety assessment. Under a...