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Participation at the 2021 Annual Meeting of the American Society for Cellular and Computational Toxicology is Complimentary This Year!
August 2, 2021As we are once again meeting online, we are pleased to announce that access to the 2021 meeting will be FREE for all attendees. However, if you are interested in helping further ASCCT’s activities, please consider becoming a member—one-year memberships for students are only $20 USD, and individual memberships are $50 USD. By joining as a member, you will have early-bird access to register for our monthly webinars, as well as receive exclusive industry-specific job postings and other relevant opportunities shared...
IIVS e-News – July 2021
June 30, 2021The Defined Approaches (DAs) to Skin Sensitization Test Guideline cites 2 strategies which can be used to evaluate hazard potential of compounds and 1 strategy to evaluate GHS potency. The hazard DAs involve in vitroapproaches to the evaluation of sensitization using multiple assays which evaluate different steps in the Adverse Outcome Pathway. Both the "2 out of 3" (Fig 1) and "Key Event 3/1" approaches (Fig 2) have been included in the OECD Test Guideline. The potency assessment is an...
IIVS e-News – May 2021
May 6, 2021IIVS and the Research Institute for Fragrance Materials (RIFM) have initiated a collaboration to develop tests designed to assess potential respiratory allergens. Developing a reliable, in vitroassay to assess the allergenicity of materials to the airway tract has been an area of active research for well over a decade, however most efforts have resulted in poor accuracy and the inability to distinguish airway sensitizers from irritants. By combining the extensive expertise and knowledge base in the field of respiratory toxicology...
How a GIVIMP Certification Program Can Increase Confidence in In Vitro Methods
April 20, 2021Regulatory bodies, validation authorities, method developers, and industry toxicologists realize the need to increase confidence in the scientific validity of novel in vitro methods – especially those being proposed for regulatory application ....
IIVS Co-Publishes Article on Ocular Animal Model Alternatives
April 20, 2021The human eye may be exposed to chemicals through various situations, such as accidental splashing or exposure to chemical particles, vapours or gases. Workers and consumers are usually advised to immediately wash eyes generously with water following exposure....
IIVS to collaborate with RIFM to develop non-animal technologies for respiratory allergy
March 31, 2021The Institute for In Vitro Sciences (IIVS) and the Research Institute for Fragrance Materials (RIFM) announce a collaboration to develop a non-animal (in vitro) test designed to assess potential respiratory allergens....
Acute Electronic Vapour Product Whole Aerosol Exposure of 3D Human Bronchial Tissue
March 2, 2021IIVS is excited to have taken part in a new publication highlighting the use of non-animal methods to compare cellular and molecular responses of tobacco smoke and Electronic Vapor Product aerosols. Read and Download the open access article here....
Validation of the 3D RSMN Assay
February 10, 2021IIVS is excited to have taken part in the validation of the Reconstructed Skin Micronucleus Assay as a big step towards the establishment of an OECD test guideline. Read the Full Article Here...
IIVS, RIFM and Shiseido Partner to Transfer Non-animal Photosafety Tests
July 14, 2020The Institute for In Vitro Sciences (IIVS) has entered into an agreement with Shiseido and the Research Institute for Fragrance Materials (RIFM) to support the technology transfer of non-animal tests for photosafety testing. The program aims to build upon IIVS’ current photosafety tiered testing program, which addresses photoirritation, through the development of additional testing strategies to identify photoallergens. Both photoirritation and photoallergenicity are important in the safety assessment of fragrances. RIFM, Shiseido, and IIVS share the common goal of promoting the...
IIVS’ Outreach Program for Non-animal Test Methods Supported by Chinese Cosmetic Company
June 22, 2020June 23, 2020, Gaithersburg, MD - US based non-profit Institute for In Vitro Sciences Inc. (IIVS) has received its first funding from a Chinese owned and operated beauty tech company, Shenzhen Basixing Technology Co., Ltd. The occasion is significant as it demonstrates the growing desire for non-animal test methods in China and the importance of the IIVS program to help implement them. Shenzhen Basixing Technology (Shenzhen, China) focuses on the application of new technologies in both beauty care products and devices....