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Respiratory Toxicology for Pharmaceutical Development
May 6, 2020The Institute for In Vitro Sciences (IIVS) provides robust test systems and assays to detect the adverse effects of diverse materials, including pharmaceuticals targeting COVID-19. The IIVS Respiratory Toxicology Program offers testing services using cutting edge 3D pulmonary models - in addition to human 2D primary cells and lines - such as reconstructed human airways and precision-cut human lung slices that contain multiple cell types including immune competent macrophages. These systems allow the detection of acute toxic responses such as...
FDA Releases New Guidance Recommending Alternatives to LLNA
April 22, 2020FDA releases new guidance recommending the performance of alternative test methodologies in lieu of the murine-based Local Lymph Node Assay (LLNA) to assess skin sensitization potential for topically-applied drug products. This information can be found at https://www.fda.gov/media/135312/download, pages 7-8. IIVS offers multiple assays and provides guidance to companies and organizations interested in using non-animal approaches to evaluate this endpoint. Learn more about our skin sensitization testing capabilities at https://iivs.org/testing-services/assays/sensitization/ or contact us at clientservices@iivs.org....
Phototox and BCOP Russian Translations
February 25, 2020IIVS, in collaboration with EPAA, is pleased to announce that our training videos for eye irritation and phototoxicity are now available with Russian subtitles. To view subtitled versions in different languages including Chinese, Portuguese and Spanish, please visit our YouTube channel. ...
2020 SOT Enhancement of Animal Welfare Award Announced
January 23, 2020IIVS offers our congratulations to Kristie Sullivan, Vice President for Research Policy with the Physicians Committee for Responsible Medicine, who has been awarded the 2020 SOT Enhancement of Animal Welfare Award by the Society of Toxicology for "her influence in advancing science and policy to reduce or replace the use of animals in testing without compromising public health". Kristie is a frequent collaborator with IIVS in our joint mission to replace animal testing with new approach methodologies and we are pleased...
US EPA Commits to Dramatically Reduce Animal Testing
September 13, 2019The US EPA has committed to dramatically reducing animal testing with a commitment for total elimination by the year 2035. IIVS is proud to have played a part in the move to reduce animal testing, starting with the successful development, and acceptance, of the non-animal eye-irritation defined approach, which was developed by an industry and regulatory consortium led by IIVS' CEO Rodger D. Curren, Ph.D. IIVS looks forward to continuing its collaboration with stakeholders to help the agency achieve its goals. Read the...
IIVS Receives Support for Non-Animal Testing From RIFM
September 9, 2019September 10, 2019, Gaithersburg, MD – The Institute for In Vitro Sciences, Inc. (IIVS) is excited to announce that it has received a grant from the Research Institute for Fragrance Materials (RIFM) to support its mission to promote non-animal methods. The grant will be used to purchase equipment that will enable IIVS to expand capabilities and offer several non-animal tests in compliance with Good Laboratory Practices. “RIFM and IIVS have a long history of working together to identify non-animal testing approaches...
PETA Science Group and Tobacco Companies Donate to Save Animals
August 28, 2019Donated Equipment Will Help to Replace Animals in Respiratory Toxicity Testing Gaithersburg, MD — The PETA International Science Consortium Ltd., Imperial Brands PLC, Altria Client Services (ALCS), British American Tobacco PLC, and Philip Morris International Inc have joined together to donate equipment that can help to replace the use of animals in respiratory testing with more human-relevant, non-animal test methods. The equipment — worth $110,000 and manufactured by Germany-based VITROCELL Systems — was donated to the Institute for In Vitro Sciences (IIVS),...
Register Now for 2020 Practical Methods for In Vitro Toxicology Workshop
August 22, 2019Register Now! Registration is open for our 2020 Practical Methods for In Vitro Toxicology Workshop which will be held at our facilities in Gaithersburg, Maryland, USA, and will begin on Monday afternoon, January 13, and finish on Thursday afternoon, January 16. This intensive workshop includes presentations from IIVS scientists and guest speakers. In addition, attendees will benefit from valuable hands-on experience working with in vitro techniques in the laboratory. The workshop is suitable for both those who are just beginning to use...
See You at EUROTOX 2019!
August 15, 2019IIVS is excited about meeting attendees of the 55th EUROTOX conference! Please join us at booth #34 to meet our representatives who are looking forward to discussing trends and New Methodologies in Alternative Approaches (NAMs) to toxicological research, as well providing updates on services offered by our organization! Also, don’t miss our posters: The kinetic Direct Peptide Reactivity Assay (kDPRA): An in chemico method to characterize the skin sensitization potency of chemicals (Poster Viewing 1) Increased Throughput and Cryopreservation of Precision-Cut Lung...
IIVS and Partners Win Contract from the European Commission to Develop Training for Non-animal Testing Methods
July 16, 2019July 16, 2019, Gaithersburg, MD – The Institute for In Vitro Sciences (IIVS) is pleased to announce it is part of a winning consortium, headed by SYRCLE (the Systematic Review Centre for Laboratory animal Experimentation), to develop interactive eLearning training modules. The application of the Replacement, Reduction and Refinement of animal testing, commonly known as “The 3Rs,” is a requirement in the European Union Directive 2010/63/EU “on protection of animals used for scientific purposes.” Training is an essential component to...