March 2016

Evaluation of New Solvents for the Use in the Multi‐Dose Reconstructed Human EpiDermis (RhE) Phototoxicity Assay

March 17, 2016
The phototoxic potential of test materials after exposure to UVA/visible light is evaluated by the 3T3 Neutral Red Uptake Phototoxicity Assay using Balb/c 3T3 mouse fibroblasts (OECD TG 432). To address challenges related to testing of finished products or materials that are not completely soluble, the Reconstructed Human EpiDermis (RhE) Phototoxicity Assay (INVITTOX Protocol 121) can be used as a stand‐alone or in a tiered approach. Water and sesame oil were recommended solvents for the RhE Assay, however additional solvents... 3T3 Neutral Red Uptake | Cosmetic & Personal Care | Fragrance & Flavors

SOT 2016 Skin Sensitization Poster

March 15, 2016
Source: SOT 2016... DPRA | Integrated Testing Strategies | Agro/Petrochemical | Cosmetic & Personal Care | Fragrance & Flavors | Occupational Safety & Industrial Hygiene | Specialty Chemical

SOT 2016 Clorox Poster

March 15, 2016
Source: SOT 2016... BCOP | Eye Irritation Test | Household & Consumer Products

Effect of Acclimation Conditions on 3D Human in vitro ALI Airway Models: Exposure-induced Inflammatory Response and Sampling Location-specific Results

March 15, 2016
Source: SOT 2016... Acute Respiratory Toxicity | Bronchial/Tracheal | Household & Consumer Products | Tobacco

2014 CORESTA: Toxic Insult to Rat Precision Cut Lung Slices

March 10, 2016
Source: CORESTA 2014... Bronchial/Tracheal | Precision Cut Lung Slices (PCLS) | Pulmonary Models | Household & Consumer Products | Tobacco

2014 TSRC Lung Slices for COPD

March 10, 2016
Source: TRSC 2014... Bronchial/Tracheal | Chronic Respiratory Toxicity | Tobacco

Overview: Etiology of COPD and In Vitro Models

March 10, 2016
... Bronchial/Tracheal | Chronic Respiratory Toxicity | Tobacco

Detection of Inflammation and Parenchymal Damage Using Precision-cut Lung Slices

March 10, 2016
... Bronchial/Tracheal | Precision Cut Lung Slices (PCLS) | Pulmonary Models | Household & Consumer Products | Tobacco

3D Reconstructed Human Airway Models: Effect of Acclimation Conditions on Biomarker and Inflammatory Response Following Tissue Challenge

March 10, 2016
Source: TRSC 2015... Acute Respiratory Toxicity | Bronchial/Tracheal | Tobacco

IIVS e-News, March 2016

March 1, 2016
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