Archive

20 Jan Respiratory Toxicology

Posted at 04:13h in by Mitchell Gaydash 0 Comments

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="center" background_image_as_pattern="without_pattern" z_index=""][vc_column][button target="_self" hover_type="default" text_align="center" text="Learn More About Human Precision Cut Lung Slice Services and Purchase" link="https://iivs.org/assays/respiratory-toxicology-2/test-systems/3d-pcls/" background_color="#19388a" hover_background_color="#ffffff" color="#ffffff" hover_color="#303030"][vc_empty_space height="16px"][button target="_self" hover_type="default" text_align="center" text="LEARN ABOUT THC and CBD PRODUCT TESTING" link="https://iivs.org/assays/respiratory-toxicology-2/cbd-thc-product-testing/" background_color="#c60751" hover_background_color="#ffffff" color="#ffffff" hover_color="#303030"][vc_empty_space][/vc_column][/vc_row][vc_row css_animation=""...

13 Sep kDPRA: An in chemico Method to Characterize the Skin Sensitization Potency of Chemicals

Posted at 11:11h in Uncategorized by Jane Ryan 0 Comments

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While the skin sensitization hazard of substances can readily be identified using non-animal methods, the classification of potency into UN GHS sub-categories 1A and 1B remains challenging. The kinetic direct peptide reactivity assay (kDPRA) is a modification of the DPRA (OECD TG 442C) wherein the...

15 Aug See You at EUROTOX 2019!

Posted at 10:42h in Featured Post by Jane Ryan 0 Comments

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IIVS is excited about meeting attendees of the 55th EUROTOX conference! Please join us at booth #34 to meet our representatives who are looking forward to discussing trends and New Methodologies in Alternative Approaches (NAMs) to toxicological research, as well providing updates on services offered...

10 Jan Register For ICCVAM’s Free Webinar on In Vitro Inhalation Toxicity Testing

Posted at 15:04h in Uncategorized by Jane Ryan 0 Comments

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NICEATM will organize a free webinar on behalf of ICCVAM on January 22, 2019 between 1:00-2:30 p.m. Eastern Time. Registration will be required. Topics will include an overview of ongoing collaborative efforts, as well as the presentation of a case study on refining inhalation risk assessment...

18 Oct ARE-Nrf2 Luciferase Keratinocyte Activation Test Method (OECD 442D)

Posted at 17:22h in by Jane Ryan 0 Comments

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text]KeratinoSens^TM is a cell-based reporter gene assay that models the second key event in the Adverse Outcome Pathway for Dermal Sensitization (keratinocyte activation). The assay measures the induction of a stably transfected luciferase gene under the control of the antioxidant response element (ARE) derived from the human AKR1C2 gene.

04 Oct IIVS Hosts Quarterly Meeting for SQA’s Computer Validation and IT Compliance (CVIC) Specialty Section

Posted at 12:23h in Uncategorized by Jane Ryan 0 Comments

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The CVIC agenda included a presentation and follow-up discussion on artificial intelligence and computer learning and their use in regulated industry, a panel discussion of cloud computing adoption in “GxP” environments, and open discussion on the use of the “Internet of Things” and data integrity and...

02 Oct Encouraging Regulatory Acceptance of Non-Animal Testing Methods Discussed at Annual SACATM Meeting

Posted at 14:37h in Uncategorized by Jane Ryan 0 Comments

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Among the topics discussed at the annual Scientific Advisory Committee on Alternative Toxicological Methods (SACATM) meeting held in early September was ways to encourage both regulators and regulated industry to use new approach methodologies (NAMs). The meeting brought together experts from academia, industry, and animal welfare organizations...

17 Sep Strategies for Eye Irritation Testing

Posted at 16:38h in by Jane Ryan 0 Comments

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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text]Determination of ocular irritation potential is a key toxicological endpoint required to support chemical and raw material characterization and industrial hygiene, to guide product development, and to achieve final product safety standards. IIVS possesses extensive experience with numerous test methods and testing strategies for commercial, industrial and regulatory applications. From standard regulatory hazard assessments to providing information on the degree of ocular irritation, to discriminating among extremely mild eye area products, IIVS’ Study Directors take the time to understand your specific goals and apply the most relevant, cost-effective strategies to achieve them.

27 Jul Modernization of EPA “6-Pack” of Acute Toxicity Tests Continues

Posted at 16:04h in Uncategorized by Jane Ryan 0 Comments

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The US Environmental Protection Agency (US EPA) continues to drive significant efforts in the United States to modernize the battery of acute toxicity tests classically known as the “6-pack.” Learn More....

26 Jul Defined Approaches for EPA Testing

Posted at 21:19h in by Jane Ryan 0 Comments

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[vc_row row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css_animation=""][vc_column][vc_column_text]The US Environmental Protection Agency (US EPA) continues to drive significant efforts in the United States to modernize the battery of acute toxicity tests classically known as the “6-pack.” Known for many years as an “all in vivo”...