Archive
Shipping Study to Evaluate the Performance of the LabCyte EPI-MODEL 24 Tissues for Use in the Skin Irritation Test (OECD TG 439) After Long-Haul Airfreight
March 18, 2019It is recommended that an evaluation of the impact of shipping of Reconstructed human Epidermis (RhE) tissues be conducted especially after long-haul airfreight shipments. The OECD Test Guideline 439 (OECD TG 439), In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method, recommends that users do so by verifying the barrier properties of the tissues after receipt. In this study, LabCyte EPI-MODEL 24 tissues were received in the USA after an overnight shipment from Japan and were tested to evaluate their performance...
Video: The 3T3 Neutral Red Uptake Phototoxicity Test
October 31, 2018This training video explores a cell-based method for assessing Phototoxicity — or the potential for chemicals to cause damage after being exposed to light. The method is used widely around the world by many industries, including the cosmetics and pharmaceutical sectors. Disclaimer: Please note that the procedures shown in this video were for demonstration purposes only and that all assay procedures, except the UV A/dark exposure, should be performed in a biological safety cabinet using aseptic techniques. Due to video production reasons,...
IIVS Hosts Quarterly Meeting for SQA’s Computer Validation and IT Compliance (CVIC) Specialty Section
October 4, 2018The CVIC agenda included a presentation and follow-up discussion on artificial intelligence and computer learning and their use in regulated industry, a panel discussion of cloud computing adoption in “GxP” environments, and open discussion on the use of the “Internet of Things” and data integrity and governance concepts. In addition to the CVIC member, an FDA representative was on site to gather industry input on specific topics. IIVS is pleased to support activities like this through the Society of Quality Assurance. If...
Encouraging Regulatory Acceptance of Non-Animal Testing Methods Discussed at Annual SACATM Meeting
October 2, 2018Among the topics discussed at the annual Scientific Advisory Committee on Alternative Toxicological Methods (SACATM) meeting held in early September was ways to encourage both regulators and regulated industry to use new approach methodologies (NAMs). The meeting brought together experts from academia, industry, and animal welfare organizations and the importance of collaboration among the different groups and geographical regions was a recurring theme. Learn more...
Tiered In Vitro Testing Strategy For Assessing The Ocular and Dermal Irritation/Corrosion Potential of Pharmaceutical Compounds
July 23, 2018Read our latest publication with Bristol-Myers Squibb regarding a tiered testing strategy for occupational hazards of pharmaceutical intermediates now published in the Cutaneous and Ocular Toxicology Journal. Irritation reactions are a frequently reported occupational illness. The potential adverse effects of pharmaceutical compounds (PCs) on employees' eyes and skin can now be assessed using validated in vitro methods. Our overall aim is to reduce animal testing by replacing the historically utilized in vivo test methods with validated in vitro test methods which accurately determine the ocular...
Abstract Deadline Extended for EUSAAT 2018
June 21, 2018The 21st European Congress on Alternatives to Animal Testing & 18th Annual Congress of EUSAAT (European Society for Alternatives to Animal Testing) will take place in Linz, Austria, 23-26 September. Submission deadlines for both oral and poster presentations have been extended to July 6. Erin Hill and Rodger Curren from IIVS are both speaking at the event. Learn more about the meeting, including the scientific program, invited speakers, and how to register. ...
Abstract Deadline Extended for ESTIV 2018
June 18, 2018The 20th International Congress on In Vitro Toxicology (ESTIV2018) happening in Berlin, 15-18 October, has extended their abstract submission deadline to July 1. Several grants and bursaries are also still open to applicants until July 1, including the PETA International Science Consortium early-career scientist award. Learn more about the meeting, including the scientific program, invited speakers, and how to register. ...
View our Posters from SOT 2018
March 28, 2018Thank you to all who visited our booth at the 2018 SOT meeting. Our scientists presented several posters at the meeting. If you did not have an opportunity to view our posters, or would like to view them again, we now have them available here to view online. ...
IIVS at SOT 2018
February 8, 2018IIVS will have several events and posters at the upcoming SOT meeting, March 11-15, in San Antonio, TX. The events and three of our five posters focus on our respiratory toxicology program in support of our new laboratory that opened in 2017. Other posters examine topics in phototoxicity. Be sure to visit our booth at the meeting - Booth #533. View more details on our events and posters at SOT....
Reducing the Use of Animals in Safety Testing: Strategic Roadmap Released
February 1, 2018The National Toxicology Program, in collaboration with other US federal agencies, has published a strategic roadmap offering a new framework for the safety testing of drugs & chemicals aimed at reducing the use of animals. Read more....