March 18, 2019
The selection of reference and proficiency chemicals is an important component of method validation and proficiency evaluations. Reference chemicals are a set of test substances used by a method developer to evaluate there liability and relevance of a new method, in comparison to reference data (usually to a validated reference method). Proficiency chemicals, as defined in OECD Guidance Document on Good In Vitro Method Practices, are defined post validation as a subset of the reference chemicals, or other chemicals with...
BCOP | Corrositex | BASF SE | Erin Hill | GIVIMP | Good In Vitro Method Practices | Hans Raabe | Robert Landsiedel | SOT 2019 | Susanne Kolle
August 16, 2016
Pharmaceutical companies can use in vitro testing for assessing worker safety. Pharmaceutical intermediates should be evaluated to determine the primary hazards associated with them so that those involved in the manufacturing process can take necessary precautions to avoid hazardous exposures.
Pharmaceutical compounds can vary widely in their physical forms, such as powders, liquids, and creams. Many in vitro assays such as those using 3-dimensional tissue constructs, and the Bovine Corneal Opacity and Permeability (BCOP) Assay, are suitable for testing different test...
3T3 Neutral Red Uptake | BCOP | Corrositex | DPRA | Eye Irritation Test | h-CLAT | Skin Irritation Corrosion Screening | Skin Irritation Test | Tissue Models | Pharmaceutical