Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS | alternative methods
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alternative methods Tag

Colombia and Canada Move Toward Animal Testing Ban

April 18, 2019
The past seven days saw both Colombia and Canada make strides towards banning animal testing for cosmetics. In Colombia, the House of Representatives unanimously approved a bill to prohibit the use of animals in testing for both cosmetics and personal care products. The bill will now move to the Senate for a vote. If approved there, the law would come in to affect within a year of the vote. A promising first step was taken in Canada where a bill advocating for...

Illinois’ Senate Bans Sale of Cosmetics Tested on Animals

March 28, 2019
The Illinois state Senate has passed a bill which would amend the state's Food, Drug and Cosmetics Act to include a ban on the sale or import of cosmetics that have been tested on animals. Overall, the bill is in line with the California Act which is currently the most stringent law within the U.S. The Illinois bill is now being considered by the state's House of Representatives....

Video: The 3T3 Neutral Red Uptake Phototoxicity Test

October 31, 2018
This training video explores a cell-based method for assessing Phototoxicity — or the potential for chemicals to cause damage after being exposed to light.  The method is used widely around the world by many industries, including the cosmetics and pharmaceutical sectors. Disclaimer:  Please note that the procedures shown in this video were for demonstration purposes only and that all assay procedures, except the UV A/dark exposure, should be performed in a biological safety cabinet using aseptic techniques. Due to video production reasons,...

IIVS Appointed to China’s Alternatives Working Group for Cosmetics

October 9, 2018
Gaithersburg, MD – October 9, 2018 – U.S. based Institute for In Vitro Sciences (IIVS) has been invited by China’s National Institute for Food and Drug Control (NIFDC) to join their working group on alternatives for cosmetics.  The newly established group was announced by the NIFDC during their 2nd International Conference on Cosmetics Alternative Methods held in Beijing in September.  Chaired by NIFDC Vice Director, Lu Yong, the working group also includes representatives from several provincial government agencies and companies...

Webinar: Precision-cut Lung Slices

October 5, 2018
Dr. Holger Behrsing, Principal Scientist with IIVS, recently presented "Precision-cut Lung Slices (PCLS)" for the 2018 PETA International Science Consortium webinar series on non-animal inhalation testing methods. ...

The Assessment of Phototoxicity Using the 3T3 Neutral Red Uptake (NRU) Phototoxicity Assay and a Modified Photo-Direct Peptide Reactivity Assay (DPRA)

March 28, 2018
Alternative methods, including the validated 3T3 Neutral Red Uptake (NRU) Phototoxicity assay (OECD TG 432) may be used as a pre-clinical test to address phototoxicity. Currently, there are no validated alternative test methods to identify photoallergens; however, there are several validated alternative test methods to address skin sensitization, including the Direct Peptide Reactivity Assay (DPRA) (OECD 442C). To address photoallergy, we utilized the 3T3 Phototoxicity assay in combination with a modified photo-DPRA assay to determine if these assays were able...

Video: The 3T3 Neutral Red Uptake Phototoxicity Test – Spanish

October 6, 2017
This new training video explores a cell-based method for assessing Phototoxicity — or the potential for chemicals to cause damage after being exposed to light. The method is used widely around the world by many industries, including the cosmetics and pharmaceutical sectors. Disclaimer: Please note that the procedures shown in this video were for demonstration purposes only and that all assay procedures, except the UV A/dark exposure, should be performed in a biological safety cabinet using aseptic techniques. Due to video production...

Video: The 3T3 Neutral Red Uptake Phototoxicity Test — Chinese

November 21, 2016
This training video with Chinese subtitles explores a cell-based method for assessing Phototoxicity — or the potential for chemicals to cause damage after being exposed to light. The method is used widely around the world by many industries, including the cosmetics and pharmaceutical sectors. Disclaimer: Please note that the procedures shown in this video were for demonstration purposes only and that all assay procedures, except the UVA/dark exposure, should be performed in a biological safety cabinet using aseptic techniques. Due to...

Video: The 3T3 Neutral Red Uptake Phototoxicity Test — Portuguese

November 21, 2016
This new training video with Portuguese subtitles explores a cell-based method for assessing Phototoxicity — or the potential for chemicals to cause damage after being exposed to light. The method is used widely around the world by many industries, including the cosmetics and pharmaceutical sectors. Disclaimer: Please note that the procedures shown in this video were for demonstration purposes only and that all assay procedures, except the UV A/dark exposure, should be performed in a biological safety cabinet using aseptic techniques....