Non Animal Testing, Alternative Test Methods, In Vitro Toxicology, IIVS | 2016 November
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November 2016

PETA Int’l Science Consortium Announces Chance to Win a $100,000 Award

November 29, 2016
PETA is accepting proposals to award a VITROCELL® exposure system—valued at up to $100,000—to researchers who will use it to avoid testing on animals. The VITROCELL exposure system can be used to deliver aerosolized test substances to human lung cells to predict human health effects more accurately than tests on animals. DEADLINE: March 30, 2017.  The PETA International Science Consortium is also purchasing similar equipment for IIVS in support of our efforts to replace animals in inhalation testing.  Read more....

What Does China’s Approval of the First Contemporary Non-Animal Testing Method Mean for Cruelty Free Cosmetics?

November 22, 2016
IIVS' work with the China Food and Drug Administration (CFDA) and its subsidiary body, the National Institute for Food and Drug Control (NIFDC) has paid off with the recent approval of the T3 Neutral Red Uptake Phototoxicity Test, the first  non-animal test method that can be used for safety tests in cosmetics sold in China. This article references IIVS's work with the CFDA and NIFDC over the last several years to provide training and education around non-animal methods for safety...

Decoding and Modulating the Color of Human Skin

November 22, 2016
The constitutive color of human skin varies widely across the globe, from the very pale as in Celtic skin to the very dark present in regions such as sub-Saharan Africa. There is a biologic player “hard at work” producing the pigments that generate great variations in human skin color and is the protagonist of this article. It is the melanocyte. Read the full article.  ...

IIVS Holds Workshop for University of Maryland Students

November 21, 2016
IIVS hosted its fourth annual toxicology workshop for students from the University of Maryland College Park chapter of the Biomedical Engineering Society (BMES UMD).  The workshop, held on Nov. 19 at IIVS in Gaithersburg, MD, featured a combination of lectures, demonstrations and hands-on laboratory sessions introducing the students to the concepts of adverse outcome pathways and approaches to predict skin sensitization, in vitro test methods using tissue engineered models, and assays addressing ocular irritation. The workshop concluded with a career...

Video: The 3T3 Neutral Red Uptake Phototoxicity Test — Chinese

November 21, 2016
This training video with Chinese subtitles explores a cell-based method for assessing Phototoxicity — or the potential for chemicals to cause damage after being exposed to light. The method is used widely around the world by many industries, including the cosmetics and pharmaceutical sectors. Disclaimer: Please note that the procedures shown in this video were for demonstration purposes only and that all assay procedures, except the UVA/dark exposure, should be performed in a biological safety cabinet using aseptic techniques. Due to...

Video: The 3T3 Neutral Red Uptake Phototoxicity Test — Portuguese

November 21, 2016
This new training video with Portuguese subtitles explores a cell-based method for assessing Phototoxicity — or the potential for chemicals to cause damage after being exposed to light. The method is used widely around the world by many industries, including the cosmetics and pharmaceutical sectors. Disclaimer: Please note that the procedures shown in this video were for demonstration purposes only and that all assay procedures, except the UV A/dark exposure, should be performed in a biological safety cabinet using aseptic techniques....

IIVS Releases Training Video to Replace Animals in Testing

November 19, 2016
GAITHERSBURG, MD – October 12, 2016 – Funded by a grant from the European Partnership for Alternative Approaches to Animal Testing (EPAA), the Institute for In Vitro Sciences, Inc.(IIVS) has released a technical training video that describes a cell-based in vitro method for assessing phototoxicity - the potential for chemicals to cause damage after being exposed to light. The 19-minute video is the second technical training video on non-animal methods that is produced by IIVS with EPAA’s support. Both videos are...

Acceptance of First Non-Animal Method by China FDA Anticipated

November 2, 2016
GAITHERSBURG, MD – November 2, 2016 – The Institute for In Vitro Sciences (IIVS) welcomes the news from China Food and Drug Administration (CFDA) officials that – for the first time in China – data from a non-animal test method will soon be recognized for safety evaluations of cosmetics. The method, known as the 3T3 Phototoxicity assay, measures a chemical’s potential to cause harm after exposure to light. The test has undergone formal validation internationally and has been incorporated into the...