August 24, 2016 The Cytosensor Microphysiometer assay is an in vitro cellular toxicity test used to evaluate ocular irritancy. A microphysiometer is used to detect and monitor the extracellular changes in pH in L929 (mouse fibroblast) cells after exposure to a test material. Changes in the pH are caused by variations in the metabolic rate, measured indirectly as a function of changes in extracellular acidification.
Metabolism in living cells is tightly coupled to cellular ATP usage and extracellular release of acidic byproducts such as protons, lactic...Assessing Corneal Recovery | BCOP | CAMVA | Corneal Recovery Modeling | Eye Irritation Test | NociOcular Eye Sting | Ocular Irritection | Ocular Screening | Short Time Exposure | Trans-Epithial Permeability