News & IIVS Activities
New Appointment for IIVS Study Director Emilia Costin
October 18, 2016IIVS study director, Emilia Costin has joined the Scientific Advisory Board of the Romanian Center for Alternative Test Methods (ROCAM). ROCAM was established in June 2015 with the main goal to support and promote the 3Rs principles in Romania and regionally. Congratulations Emilia...
Advancing Non-animal Testing Methods: First Set of Novel Knowledge Tools Published
October 18, 2016ScienceDaily
An adverse outcome pathway, or AOP, is a highly structured way of describing a toxicological process which can lead to an adverse health effect in humans or wildlife, caused by an unsafe exposure to a chemical substance. The first five adverse outcome pathways have now been published by experts. The AOPs are novel knowledge management tools in toxicology and are useful for supporting risk ...
Momentum Grows for Modernizing the US EPA “Six-Pack” Battery of Acute Toxicity Tests
January 15, 2016In the current global regulatory climate favorable for further advancement of in vitro test methods, the US Environmental Protection Agency (US EPA) is driving significant efforts in the United States. The latest endeavor targets the modernization of the battery of acute toxicity tests classically known as the “six-pack” (Fig. 1a). Known for many years as an “all in vivo
Momentum Grows for Modernizing the US EPA “Six-pack” Battery of Acute Toxicity Tests
January 13, 2016Fig. 1a: The US EPA battery of acute toxicity tests. The blue dotted lines in association with the blue framed boxes indicate existing in vitro test methods adopted as OECD Test Guidelines and that could be considered for evaluation of their capacity. In the current global regulatory climate favorable for further advancement of in vitro test methods, the US Environmental Protection ...