Posters & Presentations
Webinar Slides: The NociOcular Assay: A Novel Assay Looking at TRPV1 Channel Activity for Eye Sting Predictions Webinar
March 14, 2014Validation and Application of the KeratinoSens Assay, a Novel In Vitro Skin Sensitization Assay
January 1, 2014Predicting Ocular Irritation of Surfactants Using the Bovine Corneal Opacity and Permeability Assay
January 1, 2014The Bovine Corneal Opacity and Permeability (BCOP) assay is an ex vivo test used to evaluate ocular irritation. According to the OECD Test Guideline (TG) 437, the BCOP assay can be used to identify chemicals which induce severe/corrosive eye irritation and those that do not require classification. However, BCOP has historically under-predicted certain anionic surfactants, when tested according to the standard liquid protocol. Since neither the basis for selecting the appropriate surfactant test methods, nor the justification for modifications are clearly presented in TG 437 or GD No. 160, we present on the testing of a few common surfactant ingredients, including sodium lauryl sulfate (SLS), Triton X-100, and benzalkonium chloride, and surfactant based formulations in the BCOP assay using standard and modified dilutions and exposures to elucidate the impact of these variables on eye irritation prediction.
Using TRPV1 Channel Activity to Predict the Eye Stinging Potential of Baby Cleansers
December 1, 2013Source: JSAAE meeting
Validation and Application of the KeratinoSens Assay, a Novel In Vitro Skin Sensitization Assay
December 1, 2013Source: JSAAE meeting
In Vitro Ocular Irritation Testing Strategy for Prototype and Final Cleaning Products
March 12, 2013Source: Presented at the 2013 Society of Toxicology Annual Meeting
CHOOSING THE APPROPRIATE SOLVENT FOR SOLID MATERIALS TESTED IN THE BOVINE CORNEAL OPACITY AND PERMEABILITY (BCOP) IN VITRO ASSAY
March 12, 2013Source: Presented at the 2013 Society of Toxicology Annual Meeting
Screening of Cosmetics Ingredients for Phototoxic Potential Using the In Vitro 3T3 Neutral Red Uptake Phototoxicity Test
March 12, 2013Source: Presented at the 2013 Society of Toxicology Annual Meeting
The inter-laboratory reproducibility of the STE test for assessing eye irritation of cosmetic products
March 12, 2013Source: Presented at the 2013 Society of Toxicology Annual Meeting
VALIDATION OF IN VITRO AND CLINICAL SAFETY ASSESSMENT OF LEAVE-ON BODY LOTIONS USING POST-MARKETING ADVERSE EVENT DATA
March 12, 2013Source: Presented at the 2013 Society of Toxicology Annual Meeting