March 2018
Oral Irritation Assessment of Electronic Liquids Using an In Vitro Oral Testing Model
March 28, 2018While data are still being collected and analyzed, there were at least 1,300 accidental electronic liquid (e-liquid) exposures reported as of 2013. Deaths have occurred as a result of ingestion of e-liquid with the effects being attributed primarily to nicotine. The Food and Drug Administration (FDA) sought to regulate e-liquid through the Tobacco Control Act passed in 2009. In 2014, the FDA issued its “Deeming” proposals for public comments, which covered e-liquid manufacturing; the Final Rule giving the FDA authority to...
Nicotine Characterization of an In Vitro Inhalation Exposure System Using Conventional and Next-Generation Tobacco Products: A US/UK Inter-Laboratory Comparison
March 28, 2018The US-FDA has regulatory authority over tobacco products, including conventional cigarettes and next generation products (NGPs) such as e-cigarettes and tobacco heating products (THPs). There is a desire by the industry, regulator and animal protection organizations to incorporate non-animal test methods for tobacco product and NGP assessment. When assessing respiratory effects in vitro, reliable exposure systems that deliver aerosols to cellular/tissue cultures at the air-liquid interface are needed....
New Studies Demonstrate Risk Reduction Potential of Heat-Not-Burn Tobacco Products and e-Cigarettes
March 22, 2018New data presented at the Society of Toxicology Annual Meeting (SOT) have demonstrated the potential of two different heat-not-burn tobacco products and e-cigarettes to reduce the risk of smoking-related diseases, in comparison to continued use of conventional cigarettes. One of those studies was by IIVS , in collaboration with PMI, that evaluated the reproducibility of three new in vitro assays. The study found that these non-animal test systems may provide may provide consistent human-relevant data corresponding to key events involved in...
IIVS at Suppliers Day 2018
March 22, 2018IIVS President, Erin Hill, and Business Development Manager, Brent Gilbert, will be at the upcoming NYSCC Suppliers Day 2018 in New York City on May 15-16. Stop by our booth (#973) to chat with us or contact us to set up a meeting....
IIVS eNews – March 2018
March 11, 2018Read the latest issue of our e-newsletter for information about our events and posters at the 2018 Society of Toxicology (SOT) Annual Meeting, presentations at upcoming meetings and more. View issue....
IIVS Names Frank Gerberick as Chief Scientific Advisor
March 1, 2018GAITHERSBURG, MD – March 1, 2018 – The Institute for In Vitro Sciences, Inc. (IIVS) announced that it has appointed Frank Gerberick, PhD as its Chief Scientific Advisor. With his expertise and knowledge of technological advances and industry trends, Dr. Gerberick will advise the organization’s governing body on scientific matters and make recommendations on future directions, such as unique research opportunities, processes to promote efficiencies, and competitive positioning for the organization. “In the current business and regulatory climate, we see the...
IIVS at SOT 2018
February 8, 2018IIVS will have several events and posters at the upcoming SOT meeting, March 11-15, in San Antonio, TX. The events and three of our five posters focus on our respiratory toxicology program in support of our new laboratory that opened in 2017. Other posters examine topics in phototoxicity. Be sure to visit our booth at the meeting - Booth #533. View more details on our events and posters at SOT....
IIVS e-News – January 2018
February 1, 2018Featured in this issue is an article on how an integrated approach to skin sensitization testing can work for your testing program. a preview of IIVS events and posters at SOT, our recent collaboration with BASF to distribute the LuSens test in China, and more. Read issue....
Know Your Skin Cells: III. The Melanocytes
February 1, 2018IIVS toxicologist and study director, Emilia Costin wrote about melanocytes, responsible for producing skin color for The Cosmetic Chemist. Read article...
Reducing the Use of Animals in Safety Testing: Strategic Roadmap Released
February 1, 2018The National Toxicology Program, in collaboration with other US federal agencies, has published a strategic roadmap offering a new framework for the safety testing of drugs & chemicals aimed at reducing the use of animals. Read more....