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31 Jul

Posted at 17:24h in by
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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text css=""]ToxTracker® is a unique, stem-cell-based assay that takes advantage of a Green Fluorescent Protein (GFP) reporter system to identify hazard and mode-of-action (MOA) of potentially genotoxic materials. ToxTracker has been extensively validated to predict in vivo genotoxic...

31 Jan

Posted at 10:50h in by
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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text css=""]The Bhas 42 CTA is used to evaluate the carcinogenic potential (tumor-initiating activity and/or -promoting activity) of genotoxic or non-genotoxic test articles. The untransformed Bhas 42 cells grow to confluence forming a density-dependent contact-inhibited monolayer. A carcinogenic...

30 Mar

Posted at 18:55h in Uncategorized by
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Regulatory restrictions on animal use have increased the reliance of risk assessors and regulators on in vitro test systems. Ideally, tissue-based assays could replace the animal studies as follow-up tools to verify results from standard in vitro assays. The RSMN assay combines the EpiDerm™ 3D reconstructed...

18 Oct

Posted at 18:45h in Uncategorized by
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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text css=""]Oct 18, 2016 This one-hour webinar, led by IIVS Director of Quality and Compliance, introduces some of the concepts of Good Laboratory Practices (GLPs) designed to promote study and data integrity within an in vitro toxicology framework. Applying these...

24 Aug

Posted at 16:59h in by
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[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text css=""]RSMN is used to evaluate the genotoxicity potential of the test article to the EpiDerm™ Skin Model. Genotoxicity potential is determined by assessing whether the micronucleus frequency in tissues exposed to the test article showed a...

24 Aug

Posted at 15:00h in by
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[vc_row row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css_animation=""][vc_column width="2/3"][vc_column_text] IIVS has a long-standing history of working with various industries to help establish or utilize in vitro models for the prediction of risk and the assessment of products under development. With the Food and Drug Administration extending...

24 Aug

Posted at 14:58h in by
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[vc_row row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css_animation=""][vc_column width="2/3"][vc_column_text]Specialty chemicals are chemical products identified on the basis of their performance or function, rather than their composition. They can be single-chemical entities or formulations and cover a wide range of product categories such as consumer products,...