IIVS News

Director of CFDA, National Institute for Food and Drug Control (NIFDC) Visits IIVS

December 15, 2016

Composed of 11 technical institutes, the NIFDC is responsible for the registration and post market surveillance of drugs, traditional Chinese medicines, medical devices, food and cosmetics. In addition to inspecting and testing these products for safety, the NIFDC publishes National Reference Standards for testing methods (such as the newly published standard for the In Vitro 3T3 NRU Phototoxicity...

First Non-Animal Test Method Accepted by China FDA

December 1, 2016

IIVS and stakeholders around the world welcomed the announcement last month by the CFDA that data from a non-animal test method can now be used to substantiate the safety of cosmetics made in China. The test, known as the In Vitro 3T3 NRU Phototoxicity Test (

IIVS Holds Workshop for University of Maryland Students

November 21, 2016

IIVS hosted its fourth annual toxicology workshop for students from the University of Maryland College Park chapter of the Biomedical Engineering Society (BMES UMD).  The workshop, held on Nov. 19 at IIVS in Gaithersburg, MD, featured a combination of lectures, demonstrations and hands-on laboratory sessions introducing the students to the concepts of adverse outcome pathways and approaches to ...

IIVS Releases Training Video to Replace Animals in Testing

November 19, 2016

GAITHERSBURG, MD – October 12, 2016 – Funded by a grant from the European Partnership for Alternative Approaches to Animal Testing (EPAA), the Institute for In Vitro Sciences, Inc.(IIVS) has released a technical training video that describes a cell-based in vitro method for assessing phototoxicity - the potential for chemicals to cause damage after being exposed to light. The 19-minute ...

New Appointment for IIVS Study Director Emilia Costin

October 18, 2016

IIVS study director, Emilia Costin has joined the Scientific Advisory Board of the Romanian Center for Alternative Test Methods (ROCAM). ROCAM was established in June 2015 with the main goal to support and promote the 3Rs principles in Romania and regionally.  Congratulations Emilia...

Momentum Grows for Modernizing the US EPA “Six-Pack” Battery of Acute Toxicity Tests

January 15, 2016

In the current global regulatory climate favorable for further advancement of in vitro test methods, the US Environmental Protection Agency (US EPA) is driving significant efforts in the United States. The latest endeavor targets the modernization of the battery of acute toxicity tests classically known as the “six-pack” (Fig. 1a). Known for many years as an “all in vivo

Momentum Grows for Modernizing the US EPA “Six-pack” Battery of Acute Toxicity Tests

January 13, 2016

Fig. 1a: The US EPA battery of acute toxicity tests. The blue dotted lines in association with the blue framed boxes indicate existing in vitro test methods adopted as OECD Test Guidelines and that could be considered for evaluation of their capacity. In the current global regulatory climate favorable for further advancement of in vitro test methods, the US Environmental Protection ...