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kDPRA: An in chemico Method to Characterize the Skin Sensitization Potency of Chemicals
September 13, 2019While the skin sensitization hazard of substances can readily be identified using non-animal methods, the classification of potency into UN GHS sub-categories 1A and 1B remains challenging. The kinetic direct peptide reactivity assay (kDPRA) is a modification of the DPRA (OECD TG 442C) wherein the reaction kinetics of a test substance towards a synthetic cysteine-containing peptide is evaluated. For this purpose, several concentrations of the test substance are incubated with the synthetic peptide for several incubation times at 25°C. After...
IIVS Receives Support for Non-Animal Testing From RIFM
September 9, 2019September 10, 2019, Gaithersburg, MD – The Institute for In Vitro Sciences, Inc. (IIVS) is excited to announce that it has received a grant from the Research Institute for Fragrance Materials (RIFM) to support its mission to promote non-animal methods. The grant will be used to purchase equipment that will enable IIVS to expand capabilities and offer several non-animal tests in compliance with Good Laboratory Practices. “RIFM and IIVS have a long history of working together to identify non-animal testing approaches...
2020 Practical Methods for In Vitro Toxicology Workshop Announced
July 26, 2019Save The Dates! IIVS is pleased to announce the dates for our 2020 Practical Methods for In Vitro Toxicology Workshop which will be held at our facilities in Gaithersburg, Maryland, USA, and will begin on Monday afternoon, January 13, and finish on Thursday afternoon, January 16. This intensive workshop includes presentations from IIVS scientists and guest speakers. In addition, attendees will benefit from valuable hands-on experience working with in vitro techniques in the laboratory. The workshop is suitable for both those who...
Creation of Italian Working Group on Alternative Methods
June 18, 2019The Italian Health Ministry recently announced the creation of a working group for the promotion of alternative methods. Experts on alternative methods, along with stakeholders, will meet monthly and update the health minister every six months. The group has been tasked with a number of responsibilities, including ensuring the proper implementation of the 2013 EU ban on animal testing for cosmetics and the correct use — and adequate funding — of alternative methods. More Information: Centro3R Italian Health Ministry Press Release (in...
Toxicologist I
May 14, 2019We are seeking a full time Toxicologist I/Study Director to work in our Gaithersburg office. This is an exciting opportunity to join and grow with our team to contribute and share in our company vision: A day when methods based on humane, wisely applied science will be used by industry and the regulatory agencies to understand the true safety and efficacy of substances. Specific Responsibilities Include, but are not limited to: Participate in the management of the dermal and ocular programs. ...
European Partnership Supports IIVS Training of Chinese Scientists in Non-animal Tests
May 9, 2019Gaithersburg, MD – May 8, 2019 – The Institute for In Vitro Sciences, Inc. (IIVS) has received a grant from the European Partnership for Alternative Approaches to Animal Testing (EPAA) to support its annual training of Chinese scientists in non-animal testing methods. As part of the agreement, two scientists from BASF SE, a member of EPAA, will join IIVS to provide hands-on training in China for four non-animal approaches for skin sensitization. This training follows the recent announcement by China’s...
Post-doctoral Scientist (Respiratory Toxicology Program)
May 6, 2019We are seeking a full time Post-doctoral Scientist (who may serve in a Study Director role, as applicable) to assist in the Respiratory Toxicology Program in our Gaithersburg office. Experience/education in in vitro and/or ex vivo toxicology is required, with experience in respiratory sensitization, or immunological processes germane to the science, necessary. A background and/or familiarity with long term pulmonary disease processes (e.g. chronic inflammation, fibrosis, COPD) is highly desired. This is an exciting opportunity to join and grow with our...
Technical Writer I
April 22, 2019We are seeking a Technical Writer I (entry level) to work in our Gaithersburg office. This position is full time; approximately 30-40 hours per week. This is an exciting opportunity to join and grow with our team to contribute and share in our company vision: A day when methods based on humane, wisely applied science will be used by industry and the regulatory agencies to understand the true safety and efficacy of substances. Job Duties and Capabilities may include, but are not...
Colombia and Canada Move Toward Animal Testing Ban
April 18, 2019The past seven days saw both Colombia and Canada make strides towards banning animal testing for cosmetics. In Colombia, the House of Representatives unanimously approved a bill to prohibit the use of animals in testing for both cosmetics and personal care products. The bill will now move to the Senate for a vote. If approved there, the law would come in to affect within a year of the vote. A promising first step was taken in Canada where a bill advocating for...
Toxicologist I (Sensitization)
April 18, 2019We are seeking a full time Toxicologist I/Study Director to work in our Gaithersburg office. This is an exciting opportunity to join and grow with our team to contribute and share in our company vision: A day when methods based on humane, wisely applied science will be used by industry and the regulatory agencies to understand the true safety and efficacy of substances. Specific Responsibilities Include, but are not limited to: Participate in the management of the skin sensitizer screening program. ...