Archive
Improving Sensitivity of the NociOcular Assay to Evaluate Ion Channel Activation by Acidic Cosmetic Ingredients
April 1, 2016Source: Pan-American Conference on Alternatives ...
Improving the Accessibility and Efficiency of the Human Cell Line Activation Test
April 1, 2016Source: Pan-American Conference on Alternatives...
Mimicking Metabolism Using Human Microsomes in Two In Vitro Assays in Order to Predict the Sensitization Potential of Pro-haptens
April 1, 2016Source: Pan-American Conference on Alternatives...
The Assessment of Alternate Solvents for Use in the 3T3 Neutral Red Uptake (NRU) Phototoxicity Assay and the Influence of Solvents on the Prediction of Phototoxic Potential of Amiodarone
April 1, 2016Source: Pan-American Conference on Alternatives...
Evaluation of New Solvents for the Use in the Multi‐Dose Reconstructed Human EpiDermis (RhE) Phototoxicity Assay
March 17, 2016The phototoxic potential of test materials after exposure to UVA/visible light is evaluated by the 3T3 Neutral Red Uptake Phototoxicity Assay using Balb/c 3T3 mouse fibroblasts (OECD TG 432). To address challenges related to testing of finished products or materials that are not completely soluble, the Reconstructed Human EpiDermis (RhE) Phototoxicity Assay (INVITTOX Protocol 121) can be used as a stand‐alone or in a tiered approach. Water and sesame oil were recommended solvents for the RhE Assay, however additional solvents...
IIVS BCOP Training Video – English
November 1, 2015Nov 1, 2015 This 13-minute training video demonstrates how to perform the BCOP assay according to the Test Guidelines for the assay set forth by the Organization for Economic Co-operation and Development (OECD TG 437). The video focuses on critical steps for the assay, including handling the isolated cornea and removing the test material from the cornea at the conclusion of the exposure time....
IIVS BCOP Training Video – Chinese
November 1, 2015Nov 1, 2015 This 13-minute video demonstrates how to perform the BCOP assay according to the Test Guidelines for the assay set forth by the Organization for Economic Co-operation and Development (OECD TG 437). The video focuses on critical steps for the assay, including handling the isolated cornea and removing the test material from the cornea at the conclusion of the exposure time....
IIVS BCOP Training Video – Portuguese
November 1, 2015Novg 1, 2015 This 13-minute training video demonstrates how to perform the BCOP assay according to the Test Guidelines for the assay set forth by the Organization for Economic Co-operation and Development (OECD TG 437). The video focuses on critical steps for the assay, including handling the isolated cornea and removing the test material from the cornea at the conclusion of the exposure time....