Author: Jane Ryan

IIVS Awarded Grant to Develop Non-Animal Testing Strategy for Respiratory Sensitization

February 22, 2016
GAITHERSBURG, MD – February 22, 2016 - The Institute for In Vitro Sciences, Inc. (IIVS) has received a grant from the Research Institute for Fragrance Materials (RIFM) to develop non-animal test methods for the evaluation of fragrance materials for potential respiratory irritation and sensitization. The grant was secured in collaboration with Liverpool John Moores University and the Physicians Committee for Responsible Medicine. The proposal, “The use of a novel non-animal platform to characterize respiratory effects of fragrance materials” combines computational approaches...

Momentum Grows for Modernizing the US EPA “Six-Pack” Battery of Acute Toxicity Tests

January 15, 2016
In the current global regulatory climate favorable for further advancement of in vitro test methods, the US Environmental Protection Agency (US EPA) is driving significant efforts in the United States. The latest endeavor targets the modernization of the battery of acute toxicity tests classically known as the “six-pack” (Fig. 1a). Known for many years as an “all in vivo” testing strategy for products registered under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), the six-pack has recently been revised to...

Momentum Grows for Modernizing the US EPA “Six-pack” Battery of Acute Toxicity Tests

January 13, 2016
In the current global regulatory climate favorable for further advancement of in vitro test methods, the US Environmental Protection Agency (US EPA) is driving significant efforts in the United States. The latest endeavor targets the modernization of the battery of acute toxicity tests classically known as the “six-pack” (Fig. 1a). Known for many years as an “all in vivo” testing strategy for products registered under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), the six-pack has recently been revised to include...

IIVS e-News, January 2016

January 1, 2016
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IIVS BCOP Training Video – English

November 1, 2015
This 13- minute video demonstrates how to perform the BCOP assay according to the Test Guidelines set forth for the assay by the Organization for Economic Co-operation and Development (OECD TG 437). The video focuses on steps that are critical to the success of the assay such as handling of the isolated cornea and removal of the test material from the cornea at the conclusion of the exposure time....

IIVS BCOP Training Video – Chinese

November 1, 2015
This 13- minute video demonstrates how to perform the BCOP assay according to the Test Guidelines set forth for the assay by the Organization for Economic Co-operation and Development (OECD TG 437). The video focuses on steps that are critical to the success of the assay such as handling of the isolated cornea and removal of the test material from the cornea at the conclusion of the exposure time....

IIVS BCOP Training Video – Portuguese

November 1, 2015
This 13- minute video demonstrates how to perform the BCOP assay according to the Test Guidelines set forth for the assay by the Organization for Economic Co-operation and Development (OECD TG 437). The video focuses on steps that are critical to the success of the assay such as handling of the isolated cornea and removal of the test material from the cornea at the conclusion of the exposure time....