The tobacco industry is facing increased testing requirements for e-cigarettes and other tobacco products that entered the market after Feb. 15, 2007. Companies hope in vitro tests that use human lung cells or tissues will be sufficient to show that their new tobacco products, including e-cigarettes, significantly reduce harm and disease and benefit the population as a whole when compared with traditional cigarettes. Several of them are working with independent, third-party laboratories, including the Institute for In Vitro Sciences (IIVS), to standardize in vitro assays for respiratory toxicology so that results from one lab can be easily compared with results from another. IIVS' Holger Behrsing discusses with C&EN.
Among the topics discussed at the annual Scientific Advisory Committee on Alternative Toxicological Methods (SACATM) meeting held in early September was ways to encourage both regulators and regulated industry to use new approach methodologies (NAMs). The meeting brought together experts from academia, industry, and animal welfare organizations and the importance of collaboration among the different groups and geographical regions was a recurring theme. Learn more
California now has the most stringent cruelty-free policies in the U.S., following Governor Jerry Brown's signing of the bill banning the sale of cosmetic products and ingredients tested on animals. The California Cruelty-Free Cosmetics Act brings California in line with the EU and other global standards but still includes some exemptions for animal tests conducted to achieve compliance with other bodies, leaving some unanswered questions. Learn more
This year saw entries for the first time from Lebanon, Sri Lanka, and Turkey as the reach of the Lush Prize continues to grow. From the many entrants, reviewers have selected a shortlist of 56 projects and 17 scientists across five award categories who go through to the final judging phase. Winners will be announced in November. Learn More.
The US Environmental Protection Agency (US EPA) continues to drive significant efforts in the United States to modernize the battery of acute toxicity tests classically known as the “6-pack.” Learn More.
Yesterday, the California Senate passed the California Cruelty-Free Cosmetics Act (SB1249) bringing the state one step closer to becoming the first state in the U.S. to ban the sale of animal-tested cosmetics. The bill will now move on to the Assembly. If passed, SB1249 will outlaw the sale of all animal-tested cosmetics (including makeup, hair and skin care, and personal hygiene products) by 2020. Read more.
Our very own Holger Behrsing, PhD, will be presenting at SIVB's Annual Meeting in St. Louis. His presentation on Tuesday, June 5th is titled "Pragmatic Use of State-of-the-Art Lung Models to Evaluate Exposure-induced, Adverse Pulmonary Effects" and will provide an overview of in vitro/ex vivo pulmonary models and how they can be incorporated into a screening/testing strategy for chemicals that can include more complex human pulmonary adverse events that are evaluable in modern 3D systems. Read More
Registration is now open for the 7th Annual ASCCT Meeting - Predictive Toxicology: Strategies for Implementing New Approaches - being held September 11-12, 2018, at the National Institutes of Health in Bethesda, MD. Learn More
The non-binding resolution calls for a diplomatic push towards a global animal testing ban for cosmetics to be in place by 2023. Europe fully banned cosmetic animal testing in 2013, but it is still permitted in 80% of countries worldwide. Read article.