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Momentum Grows for Modernizing the US EPA “Six-Pack” Battery of Acute Toxicity Tests
January 15, 2016In the current global regulatory climate favorable for further advancement of in vitro test methods, the US Environmental Protection Agency (US EPA) is driving significant efforts in the United States. The latest endeavor targets the modernization of the battery of acute toxicity tests classically known as the “six-pack” (Fig. 1a). Known for many years as an “all in vivo” testing strategy for products registered under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), the six-pack has recently been revised to...
Momentum Grows for Modernizing the US EPA “Six-pack” Battery of Acute Toxicity Tests
January 13, 2016In the current global regulatory climate favorable for further advancement of in vitro test methods, the US Environmental Protection Agency (US EPA) is driving significant efforts in the United States. The latest endeavor targets the modernization of the battery of acute toxicity tests classically known as the “six-pack” (Fig. 1a). Known for many years as an “all in vivo” testing strategy for products registered under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), the six-pack has recently been revised to include...
IIVS BCOP Training Video – English
November 1, 2015This 13- minute video demonstrates how to perform the BCOP assay according to the Test Guidelines set forth for the assay by the Organization for Economic Co-operation and Development (OECD TG 437). The video focuses on steps that are critical to the success of the assay such as handling of the isolated cornea and removal of the test material from the cornea at the conclusion of the exposure time....
IIVS BCOP Training Video – Chinese
November 1, 2015This 13- minute video demonstrates how to perform the BCOP assay according to the Test Guidelines set forth for the assay by the Organization for Economic Co-operation and Development (OECD TG 437). The video focuses on steps that are critical to the success of the assay such as handling of the isolated cornea and removal of the test material from the cornea at the conclusion of the exposure time....
IIVS BCOP Training Video – Portuguese
November 1, 2015This 13- minute video demonstrates how to perform the BCOP assay according to the Test Guidelines set forth for the assay by the Organization for Economic Co-operation and Development (OECD TG 437). The video focuses on steps that are critical to the success of the assay such as handling of the isolated cornea and removal of the test material from the cornea at the conclusion of the exposure time....